PhD Position in Biomedical Research: Join our dynamic research group focusing on rare diseases associated with mutations in the Transforming Growth Factor (TGF)-B signaling pathway. The project aims to develop novel techniques using bioluminescence resonance energy transfer (BRET) to investigate TGF-B signaling in rare diseases, such as Fibrodysplasia ossificans progressiva (FOP), Pulmonary arterial hypertension (PAH), and Diffuse Intrinsic pontine glioma (DIPG). The ultimate goal is to identify drug candidates for the normalization of aberrant TGF-B signaling.
Designation: PhD Candidate
Research Area: Biomedical Research, Rare Diseases, Transforming Growth Factor (TGF)-B Signaling
Location: Institute of Health Research in Asturias (ISPA), Oviedo, Spain
Eligibility/Qualification:
- Bachelor’s degree in Biochemistry, Biology, Biotechnology, or a related field.
- Strong academic record with an average grade equal to or higher than 8.0.
- Previous expertise in cell culture and molecular cell biology techniques.
- Proficiency in English for remote interactions with the international team.
- Ability to collaborate with other European laboratories and participate in international conferences.
Job Description:
PhD Position in Biomedical Research: Rare Diseases and Transforming Growth Factor (TGF)-B Signaling
The PhD candidate will become an expert in TGF-B signal transduction, leading the development of high-throughput BRET techniques. The focus is on rare diseases resulting from TGF-B membrane receptor mutations. The candidate will work on identifying drug candidates to normalize abnormal TGF-B signaling, followed by validation through complex functional assays in vitro. The research group is situated at the Institute of Health Research in Asturias (ISPA).
How to Apply: Please send your inquiries, CV with academic grades, and a short motivation letter to: Dr. Gonzalo Sanchez-Duffhues, Group Leader “Tissue-specific BMP Signaling” Email: g.s.duffhues@cinn.es Twitter: @DrEndMT; LinkedIN: Gonzalo Sanchez-Duffhues, Duffhueslab ORCID: 0000-0002-3205-0710; Google Scholar: Gonzalo Sanchez-Duffhues Website: https://ispa-finba.es/senalizacion-bmps/
Last Date for Apply: 21 January 2024
