Postdoc – Interneuron Coding: The Institute of Biology of the Ecole Normale Supérieure (IBENS), Paris, France, is seeking a highly motivated postdoctoral scientist for a unique opportunity to contribute to a project funded by the NIH BRAIN Initiative. The research will focus on using advanced two-photon optical voltage recording to study inhibitory cerebellar microcircuits in behaving mice.
Postdoc – Random Access Two-Photon Optical Voltage Recording to Study Cerebellar Interneuron Coding in Behaving Mice
Designation: Postdoctoral Scientist
Research Area: Random access two-photon optical voltage recording to study cerebellar interneuron coding in behaving mice
Location: IBENS, Ecole Normale Supérieure, Paris, France
Eligibility/Qualification: The ideal candidate should have experience in two-photon (2P) based functional imaging, surgery, and data analysis. Motivation to work within an interdisciplinary research program is essential. Previous experience in quantitative approaches for data analysis, signal transduction, genetic strategies, cerebellar microcircuits, and electrophysiology patch clamp will be advantageous.
Job Description:
The successful candidate will:
- Develop a project using advanced two-photon fluorescence microscopy (TPFM) for in vivo voltage recording of neuronal activity.
- Probe cerebellar microcircuit input-output relationships during a postural control behavioral task.
- Utilize optical voltage recordings to gain insights into cerebellar microcircuitry functioning and sensory-motor processing.
- Contribute to the assay of improved versions of Genetically Encoded Voltage Indicators (GEVIs) developed in collaboration with Baylor College of Medicine.
Environment: The IBENS, located in the heart of Paris, is dedicated to fundamental research at the forefront of Life Sciences. The candidate will have access to dedicated optics rooms with functional microscopes, Fab Lab, mechanical workshops, surgery facilities, and computing servers.
How to Apply: Interested candidates should apply before June 2024 by sending a short motivation letter, CV, and two email contacts for references to Laurent Bourdieu (lacntbourdienens fr), Stéphane Dieudonné (dicudon@hiologie ns fr), and Vincent Villette (sincentllette@bio ens pile). Applications will be reviewed on a rolling basis.
Last Date for Apply: June 2024
For more information on research at IBENS, please visit: https://www.bens.io/en/ (teams Laurent Bourdieu and Stéphane Dieudonné).
[Table 1: Project Details]
| Research Area | Cerebellar Interneuron Coding in Behaving Mice |
|---|---|
| Number of Positions | 1 |
| Duration of Appointment | 24 months with possible extension |
| Funding Source | NIH BRAIN Initiative |
| Salary | According to CNRS rules and depending on experience |
[Table 2: Environment]
| Location | IBENS, Ecole Normale Supérieure, Paris, France |
|---|---|
| Facilities Available | Dedicated optics rooms, Fab Lab, workshops, surgery facilities, computing servers |
| Research Focus Areas | Functional genomics, developmental biology, neuroscience, ecology, and evolutionary biology |
[Table 3: Contact Information]
| Contact Person | Email Address |
|---|---|
| Laurent Bourdieu | lacntbourdienens fr |
| Stéphane Dieudonné | dicudon@hiologie ns fr |
| Vincent Villette | sincentllette@bio ens pile |
