PhD Position in Computational Neuroscience: A fully funded PhD position in Computational Neuroscience is available at TU Graz, Austria, in collaboration with the University of Regensburg, Germany. This position, supervised by Dr. Kerstin Lenk, focuses on the computational modeling of the Blood-Brain Barrier (BBB) and its role in Major Depressive Disorder (MDD). The research aims to explore sex-dependent cellular and molecular mechanisms linking a leaky BBB to MDD. The project combines in vitro, in vivo, and in silico studies, offering a multidisciplinary approach to understanding and potentially treating MDD.
Fully Funded PhD Position in Computational Neuroscience
Summary Table
| Designation | PhD Student in Computational Neuroscience |
|---|---|
| Research Area | Computational Neuroscience, Astrocytes, Blood-Brain Barrier, Major Depressive Disorder |
| Location | TU Graz, Austria (in collaboration with the University of Regensburg, Germany) |
| Eligibility | Good level of English, very good mathematical and programming skills, interest in neurobiology |
| Job Description | Develop a computational model of the BBB, multidisciplinary project combining computational modeling with in vitro/in vivo experiments |
| How to Apply | Send a single PDF file with CV and two academic references to kerstin.lenk@tugraz.at |
| Last Date to Apply | July 6th, 2024 |
Designation
PhD Student in Computational Neuroscience
Research Area
Computational Neuroscience, focusing on astrocytes, blood-brain barrier, endothelial cells, and major depressive disorder.
Location
TU Graz, Austria, in collaboration with the University of Regensburg, Germany.
Eligibility/Qualification
- Good level of English
- Very good mathematical and programming skills
- Interest in neurobiology
Job Description
The PhD student will join the Computational Neuroscience lab led by Dr. Kerstin Lenk at TU Graz. The project involves developing a computational model of the Blood-Brain Barrier (BBB) to investigate interactions among astrocytes and endothelial cells (EC) forming blood vessels. The study will focus on how astrocyte-specific signaling molecules modulate tight junctions (TJ) between EC, impacting BBB sealing properties and the transendothelial blood-brain trafficking of substances. Disruptions in these interactions are linked to brain disorders, including major depressive disorder (MDD). The project aims to understand sex-dependent mechanisms that connect a leaky BBB to MDD, using a combination of in vitro, in vivo, and in silico studies.
How to Apply
Send your application as a single PDF file to kerstin.lenk@tugraz.at. The application should include:
- Curriculum Vitae (CV)
- Contact details of two academic references
Last Date to Apply
July 6th, 2024
