Postdoc in Chemistry (M/F): The Chemistry and Biology of Metals Lab (joint lab from CEA, Univ. Grenoble Alpes, and CNRS) invites applications for a one-year postdoctoral position to advance research in luminescent lanthanide-based probes for live cell microscopy. This work is within the framework of the LANTEN project, focusing on designing peptide-lanthanide conjugates for biological imaging at near-infrared wavelengths. The successful candidate will join the “Metallopeptides” group led by Olivier Sénèque in Grenoble, France, collaborating with partners across esteemed French institutions.
Postdoc in Chemistry (M/F): Luminescent Lanthanide Complexes for Live Cell Microscopy
Designation
Postdoctoral Researcher in Chemistry
Position Details
| Detail | Description |
|---|---|
| Job Title | Postdoc in Chemistry (M/F): Luminescent Lanthanide Complexes for Live Cell Microscopy |
| Reference Code | UMR5249-OLISEN-006 |
| Number of Openings | 1 |
| Contract Type | Researcher in Fixed Term Contract (FTC) |
| Contract Duration | 12 months |
| Start Date | 1 May 2025 |
| Location | Grenoble, France |
| Proportion of Work | Full Time |
| Salary Range | €2991 to €4166 gross per month (based on experience and CNRS salary scale in force) |
| Application Deadline | 25 February 2025, 23:59 Paris time |
Research Area
- Chemistry of and for life: Design and properties of molecules of biological interest.
- Synthesis and characterization of luminescent lanthanide complexes for biological imaging.
- Coordination chemistry, peptide conjugation, fluorescence microscopy, and spectroscopy.
Location
- Workplace: Grenoble, France
The recruited postdoctoral researcher will be part of the “Metallopeptides” group of the Chemistry and Biology of Metals Lab.
Eligibility/Qualifications
- Education: Ph.D. in Chemistry.
- Experience: 1 to 4 years of postdoctoral or related research experience.
- Skills:
- Strong expertise in organic synthesis and coordination chemistry.
- Proficiency in the purification of organic compounds/biomolecules using chromatography techniques.
- Expertise in characterization methods such as NMR spectroscopy.
- Familiarity with fluorescence techniques and mass spectrometry, which will be considered an advantage.
- Motivation and prior experience in fluorescence probes and microscopy imaging are highly desirable.
Job Description
The recruited postdoctoral researcher will:
- Synthesize and characterize luminescent lanthanide-based probes (e.g., europium and ytterbium-based complexes) and evaluate them for biphotonic microscopy of live cells.
- Design and develop responsive probes for detecting specific ions like H⁺, Mg²⁺, Zn²⁺, or small biomolecules such as H₂S or HOCl.
- Perform spectroscopic studies (focusing on luminescent techniques) to characterize probes in aqueous solutions and apply them to live-cell microscopy.
- Participate in collaborative research within the LANTEN project involving partners from Brittany, Lyon, and Montpellier.
How to Apply
- Ensure your candidate profile is updated prior to applying.
- Submit applications through the assigned portal.
- Include:
- Curriculum Vitae (CV).
- Cover letter explaining your expertise and fit for the position.
- References or letters of recommendation (if required).
Note: Details for submission will align with the official CNRS application system.
Last Date to Apply
- Applications must be submitted by 25 February 2025, 23:59 Paris Time.
Work Environment
The successful candidate will integrate with the “Metallopeptides” group, operating in a multidisciplinary and collaborative research setup. The lab emphasizes fluorescence probes and microscopy imaging, in partnership with leading researchers from CEA, Univ. Grenoble Alpes, and CNRS, as well as colleagues from other key institutions in France.
This opportunity offers a dynamic research experience in a cutting-edge field of chemistry at the intersection of biology and nanotechnology.
