Postdoc Position in Structural Biology: The Istituto Italiano di Tecnologia (IIT) is looking for a qualified and motivated postdoctoral researcher to join its Molecular Modeling and Drug Discovery Research Line, coordinated by Dr. Marco De Vivo, in Genova, Italy. This position is focused on the development of novel small molecules that inhibit the growth of early-stage melanoma tumors. The successful candidate will work in a multicultural and interdisciplinary environment involving computational and experimental research in structural biology, biochemistry, and medicinal chemistry.
Postdoc Position in Structural Biology for Drug Discovery
Designation:
Postdoctoral Researcher
Job at a Glance
| Field | Description |
|---|---|
| Research Area | Structural Biology for Drug Discovery |
| Job Type | Collaboration Contract, 12 months (renewable) |
| Location | Genova, Italy (Erzelli Campus) |
| Compensation | Competitive international salary package (based on experience and expertise) |
| Additional Benefits | Private health care coverage, possible taxable income reduction (up to 90% for eligible candidates) |
Research Area:
This position focuses on structural biology, biochemistry, and the development of small-molecule inhibitors targeting early-stage melanoma tumors, supported by biophysical, enzymatic, and cellular assays.
Location:
Genova, Italy (Erzelli Campus)
Eligibility/Qualification:
Candidates must meet the following essential requirements:
- Education:
- PhD in Biology, Biochemistry, Biophysics, Biotechnology, or related fields with a strong record of research productivity.
- Technical Proficiency:
- Documented experience in structural biology.
- Expertise in molecular biology techniques (e.g., cloning, site-directed mutagenesis, PCR, western blotting).
- Familiarity with imaging techniques and quantitative image analysis.
- Skillset:
- Strong publication record based on research experience.
- Good command of both spoken and written English.
- Experience managing and mentoring junior scientists.
- Additional Skills (Highly Recommended):
- Good communication and problem-solving skills.
- High motivation to learn and a spirit of innovation.
- Excellent time and priority management skills.
- Ability to work independently and collaboratively in an interdisciplinary environment.
Job Description:
The selected candidate will contribute to ongoing research efforts in structural biology and drug discovery by performing the following tasks:
- Characterize the activity and mechanism of action of small molecules in enzyme-based assays.
- Perform protein crystallization and structure determination.
- Use mammalian cell culture techniques to assess the mechanism of action of small molecules on human cancer cell lines.
- Implement biophysical methods (e.g., ITC, MST, SPR) to study protein-protein and protein-ligand interactions.
- Apply molecular biology techniques (e.g., cloning, mutagenesis) for protein characterization.
- Quantify cellular imaging using advanced imaging and analysis techniques.
This position provides an exciting environment for innovative research with access to cutting-edge tools and facilities at IIT.
How to Apply:
Interested candidates should submit their application online including:
- A detailed CV.
- University transcripts.
- A cover letter.
- Contact details of at least two references.
Visit the IIT career page: IIT Work At
Last Date to Apply:
February 19, 2025
This position is funded by AIRC – Associazione Italiana per la Ricerca sul Cancro (Foundation for Cancer Research in Italy), specifically under Rif. 30631 – “Design and characterization of RHOA interaction inhibitors to treat early-stage melanoma tumors” (CUP J53C24004460007).
Explore the opportunity to contribute to cutting-edge scientific research while advancing your career in a world-leading institute!
