Postdoctoral Research Assistant: The University of Dundee is seeking a motivated and skilled Postdoctoral Research Assistant to join the Centre for Targeted Protein Degradation (CeTPD) within the School of Life Sciences. This role focuses on the structural biology and biophysics of protein complexes, particularly in the context of pediatric cancer drug discovery.
Designation
Postdoctoral Research Assistant
Table
| Details | Information |
|---|---|
| Reference | UOD1951 |
| Salary | £37,174 – £45,413 per annum |
| Grade | 7 |
| Contract Type | Fixed Term (12 Months) |
| Closing Date | Tuesday, 12 August 2025, 23:59 |
Research Area
The successful candidate will engage in research aimed at discovering and developing small-molecule drugs targeting oncogenic drivers in pediatric cancers.
Location
City Campus, University of Dundee
Eligibility/Qualification
- Ph.D. in structural biology, biophysics, biochemistry, chemical/molecular biology, or a related discipline.
- Highly experienced in construct design, cloning, protein expression, purification, and characterization.
- Strong experience in structural solution via X-ray crystallography and/or cryo-EM, along with biophysical binding assays.
Job Description
The Postdoctoral Research Assistant will collaborate within a multi-disciplinary drug discovery team to:
- Characterize the binding of small-molecule ligands and degraders to target proteins and E3 ligases.
- Utilize structural biology techniques (e.g., X-ray crystallography, cryo-EM) and biophysical methods (FP, TR-FRET, ITC, SPR).
- Enlighten the structure- and biophysics-guided design of novel degraders targeting specified oncogenes related to pediatric cancers.
- Work closely with the Senior Lead Scientist and other team members in a collaborative environment.
Preferred Skills
- Experience with studying PROTACs, molecular glue degraders, and structure-based drug design.
- Proficiency in biophysical techniques and assays for studying protein interactions.
How to Apply
Interested candidates can apply via the university’s recruitment portal. Please follow the instructions for either external or internal candidates to submit your application.
- For External Candidates: Apply here
- For Internal Candidates: Navigate to ‘My Recruitment’ then ‘Available Jobs’ in OneUniversity.
Last Date to Apply
Tuesday, 12 August 2025, 23:59
