Postdoctoral Fellowship in Functional Genomics: The Synthetic Regeneration and Systems Physiology Laboratory (SRSPL) at Columbia University invites applications for a Postdoctoral Fellow to lead the development of advanced functional genomics platforms for in vivo wound healing and skin immunology research.
This position offers an exceptional opportunity to work in a highly collaborative, transdisciplinary research environment at the Columbia University Irving Medical Center, with access to world-class facilities, mentorship, and professional development. The successful candidate will drive genome-wide CRISPR-based discovery efforts and publish high-impact research advancing tissue regeneration biology.
Postdoctoral Fellowship in Functional Genomics & Regenerative Biology
Summary Table
| Category | Details |
|---|---|
| Position | Postdoctoral Fellow |
| Laboratory | Synthetic Regeneration and Systems Physiology Laboratory (SRSPL) |
| Institution | Columbia University |
| Research Focus | Functional genomics, wound healing, tissue regeneration |
| Techniques | CRISPR screens, scRNA-seq, organoids, in vivo models |
| Collaboration | Stem cell, cancer, and genome research centers |
| Publications | High-impact peer-reviewed journals |
| Application Materials | CV, Letter of Intent, 3 Reference Letters |
| Application Deadline | Open until filled |
Designation
Postdoctoral Fellow – Functional Genomics & Regenerative Medicine
Research Area
- Functional Genomics
- Tissue Regeneration & Wound Healing
- Skin Immunology
- CRISPR-based Genome-wide Screening
- Organoid and In Vivo Mammalian Models
- Systems Physiology
Location
New York City, USA
(Columbia University Irving Medical Center campus)
Job Description
The Postdoctoral Fellow will serve as a technical and scientific lead developing innovative platforms to study tissue regeneration at organ scale. The role involves close collaboration with leading research centers including the Columbia Stem Cell Initiative, the Herbert Irving Comprehensive Cancer Center, and the Columbia Genome Center.
Key responsibilities include:
- Designing and executing in vivo gene delivery strategies and pooled CRISPR (CRISPRx) screens.
- Utilizing and improving pipelines for CRISPR-screen and RNA-seq data deconvolution.
- Validating candidate genes using molecular and cellular assays (e.g., scRNA-seq, flow cytometry, lightsheet imaging).
- Performing organoid cultures from primary tissue and induced pluripotent stem cells.
- Integrating emerging scientific literature into individual and lab-wide research strategies.
- Troubleshooting experimental challenges in collaboration with PI and lab members.
- Maintaining rigorous scientific, ethical, and laboratory safety standards.
- Writing manuscripts, reports, and grant-related research materials.
- Publishing in high-impact journals and presenting at international scientific conferences.
Eligibility / Qualification
Minimum Requirements
- PhD in Cell Biology, Molecular Biology, Genetics, Biomedical Engineering, Computational Biology, or related fields.
- Strong background in cell culture and molecular biology techniques.
- Demonstrated ability to independently design, execute, and interpret experiments.
- Proven scientific creativity, initiative, and problem-solving skills.
- Excellent written and verbal communication skills with a strong publication record.
- Ability to manage multiple projects and meet research timelines.
- Commitment to collaborative and inclusive research environments.
Preferred Qualifications
- Experience with mouse models and immune cell biology.
- Background in machine learning or computational biology.
How to Apply
Interested candidates should submit:
- Letter of Intent describing motivation to pursue postdoctoral training.
- Curriculum Vitae (CV).
- Three letters of recommendation, including one from the PhD thesis advisor.
📧 All materials should be sent to:
Woappilab [at] gmail.com
Last Date for Apply
Applications are accepted until the position is filled.
