Postdoctoral Position in Generative AI: The Bio-Engineering Systems for Therapeutics (BEST) postdoc program seeks a highly motivated candidate to conduct research on adeno-associated viruses (AAVs) for gene therapy, leveraging state-of-the-art generative models in protein design. This unique opportunity combines computational biology with experimental validation, offering a collaborative work environment with ETH Zurich and Roche Pharma Research and Early Development (pRED).
Postdoctoral Position in AAV Capsid Engineering with Generative AI
Designation:
Postdoctoral Researcher
Research Area:
Gene Therapy, Computational Biology, Bioinformatics, Generative AI, AAV Engineering
Location:
Basel, Switzerland
Eligibility/Qualification:
- PhD degree or equivalent in computational biology, bioinformatics, bio-ML, or a related quantitative field (required)
- Hands-on experience with modern generative models for proteins (required)
- Strong interest in hybrid methods combining computational and experimental techniques
- Excellent communication skills in English
Job Description:
| Responsibilities | Details |
|---|---|
| Generative Modeling | Develop and implement computational workflows for novel AAV capsid design |
| Dry-to-Wet Transition | Participate in wet lab validation (e.g., library construction, viral production, NGS screening) |
| Structural Analysis | Use computational tools to ensure designs maintain structural integrity |
| Data Integration | Process and analyze high-throughput data to refine generative models |
| Collaboration | Work jointly with teams from Roche pRED and ETH Zurich D-BSSE |
How to Apply:
Interested applicants should submit the following documents as a single PDF via the online application portal:
- Letter of motivation (max 1 page)
- CV (max 2 pages)
- Full list of publications
- 3 letters of recommendation
- Statement of research interests (max 1 page)
- Copy of doctoral degree certificate (if obtained)
Last Date to Apply:
Applications will be accepted on a rolling basis until the position is filled.
For queries, please contact:
- Prof. Dr. Basile Wicky: basile.wicky@bsse.ethz.ch
- Dr. Denis Phichith: denis.phichith@roche.com
Visit Next-gen Bioengineers for more information.
