Postdoctoral Position in Functional Genomics – University of California, San Francisco (Hsiung Lab): The Hsiung Lab at the University of California, San Francisco is inviting applications from exceptionally motivated and talented postdoctoral researchers. The lab focuses on molecular genetics and synthetic biology, aiming to understand and engineer emergent properties of genetic elements.
The team recently developed an innovative functional genomics platform using engineered CRISPR-Cas12a (published in Nature Biotechnology, 2024), enabling exploration of higher-order combinatorial genetic perturbations.
This is an exciting opportunity to work on cutting-edge CRISPR technologies and interdisciplinary research spanning genomics, tissue biology, and immuno-engineering.
Postdoctoral Position in CRISPR Synthetic Biology & Functional Genomics – University of California, San Francisco (Hsiung Lab)
📊 Position Summary Table
| Category | Details |
|---|---|
| Institution | University of California, San Francisco (UCSF) |
| Laboratory | Hsiung Lab |
| Position | Postdoctoral Researcher |
| Research Focus | CRISPR Synthetic Biology & Functional Genomics |
| Location | San Francisco, California, USA |
| Application Mode | |
| Last Date to Apply | Open Until Filled |
🎓 Designation
Postdoctoral Researcher
🔬 Research Areas
The selected candidate will develop and/or apply advanced CRISPR and functional genomics approaches in the following areas:
- Enhancer biology and epigenetics
- Tissue injury responses (fibrosis and regeneration)
- Human tissue biology models from surgical specimens
- Therapeutic cell reprogramming
- Genetic screens focused on emergent tissue properties (cell–cell interactions and spatial readouts)
- Engineering cancer cells for immune system recognition
📍 Location
San Francisco, California, USA
(Hsiung Lab, University of California, San Francisco)
✅ Eligibility / Qualification
Candidates with the following expertise are strongly encouraged to apply:
- PhD in Molecular Biology, Genetics, Genomics, Immunology, Computational Biology, or related field
- Experience in:
- Single-cell and/or spatial genomics
- Immunology / Immuno-oncology
- Genome regulation
- Liver biology
- Computational biology
- Mouse models
- Strong background in CRISPR technologies and synthetic biology (preferred)
- Demonstrated research productivity
🧪 Job Description
The Postdoctoral Researcher will:
- Design and conduct CRISPR-based synthetic biology experiments
- Develop and apply functional genomics screening platforms
- Investigate enhancer regulation and epigenetic mechanisms
- Study tissue injury responses and regeneration models
- Engineer genetic screens exploring tissue-level emergent properties
- Collaborate with junior specialists and interdisciplinary teams
- Contribute to high-impact publications and grant proposals
📧 How to Apply
Interested candidates should email the following to:
Chris Hsiung
📩 Chris.Hsiung@ucsf.edu
Please include:
- Updated CV
- Statement of research interest and alignment with the lab
- Potential start date
- Contact details for 2–3 references
⏳ Last Date to Apply
Open Until Filled
(Applications will be reviewed on a rolling basis.)
