Summary
This 36-month fully funded PhD position is available at the Développement, Adaptation, Vieillissement unit within the Institut de Biologie Paris-Seine (IBPS). The project bridges wet-lab developmental biology and multi-omics bioinformatics, using amphibian embryos (Xenopus laevis) to investigate the gene regulatory networks controlling cerebellar development and neural stem cell trajectories, with comparative analyses against mammalian data.
Fully Funded 3-Year PhD in Developmental Biology & Bioinformatics in CNRS, Paris
Offer at a Glance
| Feature | Details |
| Designation | FTC PhD student / Offer for thesis |
| Research Area | Cellular biology, development, evolution-development, reproduction |
| Location | Paris (75252 PARIS 05), France |
| Duration | 36 Months |
| Remuneration | €2,300 gross monthly |
| Expected Start Date | October 4, 2026 |
| Application Deadline | August 5, 2026 (23:59 Paris time) |
Research Area: Multi-omics and computational modeling of cerebellar gene regulatory networks in vertebrate development.
Job Description & Thesis Objectives
The selected candidate will combine developmental biology, multi-omics, and bioinformatics under the supervision of Dr. BC Durand. The research focuses on two main objectives:
- Transcriptomic Profiling: Define transcriptomic profiles, cell-state markers, and gene expression trajectories during early cerebellar development in amphibians using single-nucleus (SN) RNA-seq and SN ATAC-seq. These datasets will be compared with mammalian sets (rodents, humans, and organoids).
- Pathway Analysis: Determine how altered T Cell Factor (TCF) activity affects cell fate specification, chromatin remodeling, and progenitor maintenance in the upper rhombic lip and external granular layer.
The project features cross-collaborations with computational experts at the Curie Institute and includes access to a dedicated bioinformatics engineer.
Eligibility / Qualification
- Degree level: Master’s degree or equivalent (enabling enrollment in a Doctorate program).
- Technical expectations: Interest or experience in molecular/cellular biology, developmental embryology, or computational multi-omics data analysis (transcriptomics/genomics).
- Inclusivity: The position is open to people with a document recognizing their status as a disabled worker.
How to Apply
Applications must be submitted directly through the official French National Centre for Scientific Research (CNRS) employment portal. You can access the application form by clicking the “Apply” button on the CNRS Job Offer Page.
Last Date to Apply
August 5, 2026, by 23:59
