Summary
The Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) is seeking a highly motivated Postdoctoral Researcher to join the Molecular Mechanics of the Cardiovascular System research group led by Dr. Jorge Alegre. The position is funded under the national research project “Biochemical modulation of mechanical proteins of the sarcomere relevant to heart disease” (mProHeart; Ref: PID2023-147683NB-I00), financed by MICIU/AEI/10.13039/501100011033 and FEDER, EU.
Postdoctoral Researcher – Molecular Mechanics of the Cardiovascular System (CNIC) Spain
Designation
Postdoctoral Researcher (Investigador/a Postdoctoral)
Key Details
| Attribute | Details |
| Institution | Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) |
| Position Title | Postdoctoral Researcher |
| Research Group | Molecular Mechanics of the Cardiovascular System (PI: Dr. Jorge Alegre) |
| Project Code | mProHeart (PID2023-147683NB-I00) |
| Contract Type | Indefinite Scientific-Technical Activities Contract (Law 14/2011, Art. 23-bis) |
| Location | Madrid, Spain |
| Application Deadline | August 9, 2026 |
Research Area
Molecular mechanics and multi-omics analysis of sarcomeric proteins in cardiovascular disease.
- Primary Field: Cardiovascular Molecular Mechanics & Biophysics
- Core Topics: Sarcomere protein mechanics, cardiac disease mechanisms, molecular biology, cell culture, histology, microscopy, and complex multi-omics bioinformatics (bulk transcriptomics, sc/snRNA-seq, ATAC-seq, spatial transcriptomics, and proteomics).
Location
CNIC Headquarters, Madrid, Spain
(A 24,000 m² state-of-the-art facility equipped with cutting-edge research infrastructure).
Eligibility / Qualification
Essential Requirements
- PhD Degree: Must hold a PhD in the area of Life Sciences at the time of contract formalization.
- Publication Record: Co-authorship in at least one peer-reviewed publication in a prestigious scientific journal (in any position).
Desirable Criteria & Evaluation Scoring
- C1 – Sarcomere Mechanics Experience (30%): Proven research experience in sarcomere mechanics and sarcomeric proteins, with the ability to autonomously design and carry out research projects in this field.
- C2 – Bioinformatics & Omics Analysis (30%): Accredited experience in processing, analyzing, and bioinformatically interpreting complex omics datasets (bulk transcriptomics, sc/snRNA-seq, ATAC-seq, spatial transcriptomics, and/or proteomics) for in vitro and in vivo studies.
- C3 – International Experience (20%): Accredited international mobility through research stays abroad.
- C4 – Interview (20%): Conducted for top candidates who achieve a minimum of 70 points across criteria C1–C3.
Positive Action Measure: Candidates with a certified disability degree $>66\%$ receive a 1.5 multiplier, and those with $>33\%$ receive a 1.2 multiplier applied to experience duration calculations.
Job Description
The selected candidate will carry out the following duties:
- Design, execute, and interpret experiments to elucidate the molecular mechanisms governing the mechanical function of sarcomeric proteins in myocyte contraction.
- Utilize advanced experimental techniques, including histology, microscopy, molecular biology, cell culture, and bioinformatic analysis of complex omics data.
- Participate actively in departmental seminars, research group meetings, and scientific presentations.
- Present research findings at international scientific meetings and conferences.
- Prepare and publish high-impact manuscripts in peer-reviewed indexed journals.
- Assist with routine maintenance and organizational tasks within the laboratory and department.
How to Apply
- Go to the official CNIC Recruitment Portal Announcement.
- Click on “Crear nueva cuenta” (Create new account) to register with your email and password, or log in if you already have an account.
- Complete the candidate registration form and submit your application online.
Last Date for Apply
Sunday, August 9, 2026
