Karolinska Institutet is inviting applications for a four-year doctoral (PhD) student position focused on decoding the metastatic cascade to bone in neuroblastoma. This in vivo-intensive project aims to identify therapeutic targets for bone marrow metastases in pediatric oncology using advanced single-cell technologies and CRISPR screening.
Designation
Doctoral (PhD) Student
Key Information
| Detail | Information |
|---|---|
| Position | PhD Student |
| Institution | Karolinska Institutet |
| Research Group | Baryawno Laboratory |
| Location | Stockholm, Sweden |
| Duration | 4 Years (Full-time) |
| Application Deadline | December 9, 2026 |
Research Area
The research focuses on Pediatric Oncology and Bone Metastasis. Specifically, the project investigates high-risk neuroblastoma to understand how tumor clones colonize the bone niche. Techniques include single-cell RNA-seq, bioinformatics, immunology, molecular biology, and functional analysis using preclinical animal models.
Location
The position is based at BioClinicum in Stockholm, affiliated with the Division of Pediatric Oncology and Pediatric Surgery, Department of Women’s and Children’s Health, Karolinska Institutet, Sweden.
Eligibility/Qualification
To be eligible for this doctoral education, applicants must meet the following requirements:
General Eligibility
- A completed Master’s degree (second-cycle qualification).
- OR satisfied requirements for courses comprising at least 240 credits (with 60 credits at the advanced level).
- OR equivalent knowledge acquired in Sweden or abroad.
Specific Eligibility
- Proficiency in English equivalent to the Swedish upper secondary school course English 6/English B.
Preferred Skills
- Hands-on experience with preclinical in vivo mouse models of cancer is highly meritorious.
- Experience in molecular and cell biology, organoid culture, or CRISPR screening.
- Strong communication skills and the ability to work effectively within a research team.
Scholarship Description
The successful candidate will be employed on a doctoral studentship with a contractual monthly salary. The project, “Decoding the metastatic cascade to bone,” involves identifying metastasis-driving clones and genes through cell-barcode lineage tracing and spatial transcriptomics. Karolinska Institutet offers a creative research environment, elective courses, and access to modern health facilities/gyms.
How to Apply
Applications must be submitted through the Varbi recruitment system. The application should include:
- A personal letter and Curriculum Vitae (CV).
- Degree projects and any previous publications.
- Documentation certifying general and specific eligibility (degree certificates and English proficiency).
Apply Link: Click here to apply
Last Date for Apply
The deadline for applications is December 9, 2026.
