Doctoral (PhD) Student Position: Are you interested in contributing to cutting-edge medical research? Karolinska Institutet’s Department of Microbiology, Tumor and Cell Biology is seeking a dedicated doctoral student to join the Fossati lab in the study of bacterial immune systems, specifically toxin-antitoxin systems, as phage defense and potential antimicrobial agents. This is a unique opportunity to work on a research project under experienced supervision and with access to world-class resources.
Table:
| Designation | Research Area | Location | Eligibility/Qualification | Job Description | How to Apply | Last Date for Apply |
|---|---|---|---|---|---|---|
| Doctoral (PhD) Student | Bacterial Antiphage Systems | Solna, Stockholms län, Sweden | See below | As a doctoral student, you will work on a research project focused on the characterization of Mycobacteria toxin-antitoxin systems, specifically their role in phage defense and antimicrobial potential. You will gain hands-on experience in mass-spectrometry-based proteomics, functional and comparative genomics, and computational systems biology. Additionally, you will participate in relevant PhD courses, research seminars, and educational initiatives. | Submit your application and supporting documents through the Varbi recruitment system. Your application must contain a personal letter, a curriculum vitae, degree projects, previous publications (if any), and documents certifying your eligibility. | November 13, 2023, 11:59 PM CET |
Job Description:
Doctoral (PhD) Student Position in Characterization of Mycobacteria Toxin-Antitoxin Systems as Phage Defense and Antimicrobial Agents
The selected doctoral student will have the unique opportunity to work in the Fossati lab, a part of Karolinska Institutet’s Department of Microbiology, Tumor and Cell Biology. The focus of this research project is the characterization of Mycobacteria toxin-antitoxin systems and their potential as phage defense mechanisms and antimicrobial agents.
As a doctoral student, you will be actively involved in the following:
- Conduct mass-spectrometry-based proteomics experiments.
- Work on functional and comparative genomics research.
- Utilize computational systems biology to analyze data.
- Enroll in relevant PhD courses at Karolinska Institutet.
- Actively participate in research seminars and educational initiatives within the department.
What We Offer: As a doctoral student at Karolinska Institutet, you will be part of a creative and inspiring environment filled with expertise and curiosity. You will have access to cutting-edge resources and a well-educated supervisor. The university is a leader in medical research and education, offering a wide range of elective courses and opportunities to collaborate with prominent universities worldwide. Doctoral students receive a contractual salary, access to a modern gym, and reimbursements for medical care.
Eligibility/Qualification:
General Eligibility Requirement (A): To be eligible for doctoral education, you must meet one of the following criteria:
- Hold a second-cycle/advanced/master qualification (i.e., master’s degree).
- Have completed courses totaling at least 240 credits, with at least 60 credits at the advanced/second-cycle/master level.
- Acquire substantially equivalent knowledge through other means in Sweden or abroad.
Specific Eligibility Requirement (B): In addition to the general requirements, you must demonstrate proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.
Applicants must also possess the following skills and qualities:
- Prior experience in bacteriophage infection and isolation.
- Knowledge of bacterial culture techniques.
- Hands-on experience in basic molecular biology techniques (cloning, protein expression, protein purification, PCR, Western blot, etc).
Meritorious qualifications include:
- Prior experience in multi-protein bacterial antiphage systems (e.g., Argonaute, Gabja, Hachiman, etc).
- Proficiency in preparative and analytical PCR, site-directed mutagenesis, OE-PCR, Gibson assembly, restriction-ligation, RPA.
- Experience in NGS data analysis.
- Working knowledge of Python/R.
- Basic Unix skills.
Terms and Conditions: The doctoral student will be employed on a full-time doctoral studentship for a maximum of 4 years.
Application Process: To apply, please submit your application and supporting documents through the Varbi recruitment system. While we prefer applications in English, you may also apply in Swedish.
Your application should include:
- A personal letter and a curriculum vitae.
- Details of degree projects and previous publications, if applicable.
- Any additional documentation demonstrating the desired skills and personal qualities.
- Documents certifying your general eligibility (Requirement A).
- Documents certifying your specific eligibility (Requirement B).
Selection: Eligible applicants will be selected based on their ability to benefit from doctoral education. Evaluation will consider subject knowledge, analytical skills, and other relevant knowledge or experiences. All applicants will be informed of the selection outcome upon completion of the recruitment process.
Join Us and Make a Difference: If you are passionate about contributing to better health for all and are ready to embark on a challenging and rewarding doctoral journey, we encourage you to apply for this position. Karolinska Institutet is a world-renowned institution, and this is your opportunity to be part of groundbreaking research. Your contributions can shape the future of medical science.
Type of Employment: PhD Placement
Contract Type: Full Time
First Day of Employment: According to the Agreement
Salary: Monthly Salary
Number of Positions: 1
Full-Time Equivalent: 100
City: Solna
County: Stockholms län
Country: Sweden
Reference Number: STÖD 2-4117/2023
Contact:
- Andrea Fossati, Email: andrea.fossati@ki.se
Union Representatives:
- Henry Wölling, SEKO, Email: henry.wolling@ki.se
- Carina Eklund, OFR, Email: carina.eklund@ki.se
- Taher Darreh-Shori, SACO, Email: taher.darreh-shori@ki.se
Published: 31.Oct.2023
Last Application Date: 13 November 2023, 11:59 PM CET
Disclaimer: This job post is based on information obtained from a reliable source. For further details and to apply, please visit the official Karolinska Institutet website or the provided reference number (STÖD 2-4117/2023). The information presented here is intended as a summary and reference, and all applicants are encouraged to verify and review the details on the official site for the most up-to-date and comprehensive information.
