PhD in Biochemistry/Cell Biology: The Laboratory of Chemical Biology at KU Leuven invites applications for a PhD position focused on developing chemical probes for protease-targeting in cancer research. This interdisciplinary project integrates organic chemistry, biochemistry, and cell biology to unravel enzyme functions related to human diseases.
PhD Scholarship Opportunity in Biochemistry/Cell Biology at KU Leuven
Designation
PhD Student in Biochemistry/Cell Biology (ref. BAP-2025-500)
Research Area
- Chemical biology
- Biochemistry
- Cell biology
- Proteomics
Location
KU Leuven, Leuven, Belgium
Eligibility/Qualification
| Requirement | Details |
|---|---|
| Degree | MSc in biochemistry, cell biology, biomedical sciences, or related areas |
| Experience | Must have experience in biochemistry and cell culture techniques |
| Knowledge | Interest in bioorganic chemistry and chemical biology |
| Additional Skills | Fluorescent microscopy experience is a plus |
| Personal Attributes | Proactive problem solver, good team player, excellent English communication skills; ambitious, motivated, creative, and practically skilled |
Description
This PhD project aims to develop small molecules to degrade extracellular or membrane-bound proteases implicated in cancer by facilitating their endolysosomal uptake and destruction. Candidates will assess lysosome-targeting compounds in cell models, analyze lysosomal degradation of targeted proteases, and evaluate the effects on cancer cell phenotypes. The role offers an opportunity to collaborate with a dynamic, interdisciplinary research team and access state-of-the-art facilities.
How to Apply
Interested candidates should submit the following documents:
- Motivation letter
- CV
- Copies of MSc degree
- Copies of academic transcripts
- Contact information for at least two references
Applications should be submitted via the online application tool of KU Leuven.
Last Date to Apply
September 3, 2025, at 23:59 CET
For more information, please contact Prof. Dr. Steven Verhelst at +32 16 37 45 17 or via email at steven.verhelst@kuleuven.be.
