PhD Opportunity in Phosphate Research: Nottingham Trent University (NTU) is offering a fully funded PhD studentship aimed at investigating the role of sphingosine-1-phosphate (S1P) in obesity-associated metabolic disorders and its potential as a predictive marker for weight loss interventions. This research may provide critical insights into metabolic diseases such as type 2 diabetes, cardiovascular disease, liver disease, and asthma linked to obesity.
PhD Opportunity in Sphingosine-1-Phosphate Research
Designation
PhD Studentship – Investigating the Role of Sphingosine-1-Phosphate in Obesity-Associated Metabolic Disorders
| Detail | Information |
|---|---|
| Research Area | Health Innovation |
| Location | Nottingham Trent University, UK |
| Eligibility/Qualification | Open to UK residents, EU students, and international students with relevant qualifications |
| Funding | Fully funded |
| Starting Date | 2025 |
Description
The primary aim of this PhD research will be to explore the S1P signaling pathway in obesity and adipocyte dysfunction. The secondary aim is to investigate how dysfunctional adipocytes regulate liver disease and asthma. Key methodologies will include:
- Growing human adipocytes, hepatocytes, and airway epithelial cells.
- Gene silencing and overexpression techniques.
- Various analytical methods including immunoassays, qRT-PCR, Western blotting, fluorescent microscopy, and multi-omics approaches.
The selected student will also assess S1P metabolism in clinical samples from patients undergoing various interventions (e.g., liraglutide treatment, bariatric surgery, exercise) and utilize co-culture techniques to study intercellular communication.
How to Apply
Interested candidates should refer to the NTU application page for guidance and eligibility criteria.
Application Process:
- Visit the Nottingham Trent University applications page.
- Submit the required documentation as outlined on the webpage.
Last Date for Apply
The closing date for applications is Friday, 14 February 2025.
For further inquiries, please contact:
Gyan Tripathi
Email: gyan.tripathi@ntu.ac.uk
This PhD opportunity offers a pivotal chance for students interested in metabolic disorders research and will equip them with skills and experience for future academic or industry careers.
