PhD Position in Astrocyte Dysfunction: The Amsterdam Leukodystrophy Center is offering a PhD position focused on understanding astrocyte dysfunction in the leukodystrophy MLC. This collaborative research project aims to develop therapeutic interventions targeting MLC-related proteins to restore astrocyte function.
PhD Position in Understanding and Repairing Astrocyte Dysfunction in the Leukodystrophy MLC
Designation
PhD Candidate
Detail | Information |
---|---|
Research Area | Neurobiology, Biomedical Sciences |
Location | Amsterdam UMC |
Employment Type | Full-time (36 hours per week) |
Contract Duration | Fixed-term (12 months, with the intention to extend) |
Salary Scale | €3,017 to €3,824 gross per month |
Eligibility/Qualification
- Master’s degree in Neurosciences or Biomedical Sciences.
- Proven interest in (cellular) neuroscience, especially related to neurological diseases or astrocyte physiology.
- Article 9 qualification for animal experimentation.
- Fluent in English.
- Highly motivated and capable of working independently and in a team.
- Excellent communication skills.
Description
The project focuses on elucidating the mechanisms behind the dysfunction of astrocytes in MLC, a leukodystrophy characterized by disrupted ion and water homeostasis leading to severe neurological deficits. The selected candidate will work on characterizing new animal models and studying therapeutic interventions aimed at restoring normal function in astrocytes.
Responsibilities:
- Familiarization with astrocyte physiology and disease mechanisms related to MLC.
- Characterization of new transgenic animal models and comparison with existing ones.
- Conducting molecular and cellular studies to investigate potential therapeutic compounds.
How to Apply
Interested candidates should apply through the application portal on the Amsterdam UMC website. For more information about the application process, please contact Kim Hooijmans, Recruitment Advisor, at k.i.m.hooijmans@amsterdamumc.nl.
Last Date for Apply
December 3, 2024
For more queries about the position, please contact Rogier Min at r.min@amsterdamumc.nl. The Amsterdam UMC is committed to diversity and inclusion and encourages all interested candidates to submit their applications.