PhD Position in Bacterial Defense Systems: The Leiden University Medical Center (LUMC) invites candidates to apply for a PhD position in the exploration of bacterial defense mechanisms against viruses. This role offers the opportunity to work with cutting-edge technologies in a dynamic international environment.
PhD Position in Bacterial Defense Systems Against Viruses
Designation
PhD Candidate
Research Area
Bacterial Immunology, Molecular Biology, Biotechnology
Location
Leiden University Medical Center (LUMC), Netherlands
Eligibility/Qualification
- MSc degree in Biomedical Sciences, Molecular Biology, Biochemistry, Biotechnology, Microbiology, or a related field.
- Practical experience with molecular cloning and recombinant protein expression in prokaryotic or eukaryotic systems.
- Experience in protein purification and biochemical or biophysical characterization techniques.
- Strong interest in structural biology and motivation to learn cryo-electron microscopy (cryo-EM).
- Familiarity with bioinformatics for sequence or structure analysis, or willingness to learn.
- Programming skills (e.g., Python, Matlab) are considered an advantage.
- Effective communication skills in English, both orally and in writing.
Job Description
In this four-year PhD project, you will:
- Investigate the molecular mechanisms of bacterial antiviral defense systems.
- Conduct laboratory experiments involving cloning, protein expression, purification, and biochemical assays.
- Perform phage assays to test bacterial antiviral activity.
- Determine molecular structures using cryo-electron microscopy (cryo-EM).
- Engage in bioinformatics analyses for sequence and structure studies.
- Present research findings at conferences and publish results in peer-reviewed journals.
How to Apply
Interested candidates should send their applications, including a CV, cover letter, and relevant documents, to Luuk Loeff at the provided contact information.
Last Date to Apply
Open now