PhD Position in Computational Biophysics: The Timr group at the J. Heyrovský Institute of Physical Chemistry in Prague is offering an exciting PhD position in computational biophysics and biomolecular modeling. If you are intrigued by the intricacies of the interior of living cells and enjoy constructing models of proteins and biomolecules on a computer, this opportunity is for you!
PhD Position in Computational Biophysics and Biomolecular Modeling
Summary Table:
| Institute | J. Heyrovský Institute of Physical Chemistry |
|---|---|
| Location | Prague |
| Research Area | Computational Biophysics and Biomolecular Modeling |
| Project Focus | Dynamic Enzyme Assemblies in Living Cells |
| Starting Date | Summer 2023 (no later than October 1) |
| Type of Contract | Temporary |
| Job Status | Full-time |
Study Area: This PhD position delves into the interdisciplinary field of Computational Biophysics and Biomolecular Modeling. The focus is on understanding the physical and chemical mechanisms governing the organization of metabolic pathways in living cells.
Scholarship Description: The PhD project, titled “Computational Modeling of Dynamic Enzyme Assemblies,” explores the formation and functionality of dynamic enzyme assemblies in response to external conditions within living cells. The project employs atomistic, coarse-grained, and kinetic modeling, integrated with experimental data. The student will characterize molecular interactions, investigate substrate transfer within assemblies, and develop computational methodologies to predict metabolic fluxes. The research enhances understanding of the regulation and control of metabolic pathways, offering insights into adaptability and efficiency.
Eligibility: Candidates are expected to hold an MSc (or equivalent) in physics, chemistry, or a related field. Strong mathematical modeling skills, an interest in biomolecules, and proficiency in English are essential. Computer skills and experience with molecular simulations and programming are advantageous. Successful candidates will enroll at Charles University in Prague.
Required Documents: Interested candidates should submit:
- CV
- Motivation letter
- Transcripts of all courses and grades
- Contact information for two references
How to Apply: Send your application to recruitment@jh-inst.cas.cz and stepan.timr@jh-inst.cas.cz. In the subject line, include “SC2024_12.” In the motivation letter, align the proposed research with your interests and explain why you are a good fit for the position.
Last Date: The application deadline is 2nd April 2024. Act promptly to be considered for this exciting PhD opportunity!
Join us in unraveling the mysteries of the cell interior and advancing the field of computational biophysics and biomolecular modeling!
