PhD Position in Mitochondrial Metabolism: We are seeking a motivated student to join our ongoing research project focusing on reprogramming mitochondrial metabolism in tumor cells and its impact on their immunogenicity. The project aims to enhance the understanding of how modified tumor metabolism can make them more susceptible to immune responses.
PhD Position in Mitochondrial Metabolism and Immunogenicity
Designation
PhD Research Position
| Field | Details |
|---|---|
| Research Area | Mitochondrial Metabolism and Immunogenicity |
| Location | CNB, Madrid, Spain |
| Contact Email | smanes@cnb.csic.es |
| Deadline for Applications | 30th May |
Eligibility/Qualification
- Completed Master’s degree in Biomedicine, Molecular Biology, or a related field.
- Familiarity with the topics of mitochondrial metabolism and tumor immunogenicity.
- Permission to work with animal models and a commitment to ethical research practices.
- Proficiency in English is mandatory.
Description
This research project is led by a young PhD candidate and involves investigating several key areas:
- The signaling pathways that link mitochondrial metabolism rewiring with immunogenicity.
- The interactions of oncogenes, particularly K-Ras, with mitochondrial metabolism.
- The identification of binders of specific mitochondrial transporters.
The project will utilize advanced molecular biology methods and techniques including:
- Omics analyses (bulk or single-cell RNA sequencing, ATAC-seq, quantitative proteomics)
- CRISPR-based gene silencing
- Spectral flow cytometry
- Advanced imaging techniques
A significant portion of research will involve working with animal models, making it essential for candidates to adhere to ethical standards in animal experimentation.
How to Apply
Interested candidates should send their applications, including a CV and a cover letter detailing their research interests and motivations, to smanes@cnb.csic.es.
Last Date to Apply
Applications must be submitted by 30th May.
Join our dynamic research team and contribute to pioneering work at the intersection of biomedicine and immunology!
