This is an excellent opportunity for a highly motivated researcher to join an interdisciplinary project aimed at advancing personalized cancer therapies.
PhD Position in Nanomedicine Formulation Engineering for Cancer Treatment at TU Delft, Netherlands
Summary
The SPARC (Scalable Personalized Nanotherapeutics for Cancer Treatment) research program is seeking a PhD candidate to develop innovative lipid-based drug delivery nanoparticles. This position is a collaboration between the Precision Therapeutics group and the Complex Fluid Processing group at Delft University of Technology, focusing on designing externally triggerable nanomedicines for “cold tumors.”
Position Details
| Feature | Details |
| Designation | PhD Candidate |
| Research Area | Nanomedicine Formulation Engineering & Molecular Modeling |
| Location | Delft University of Technology (TU Delft), Netherlands |
| Salary Range | €3,059 – €3,881 gross per month |
| Duration | 4 years (initially 1.5 years, with a progress assessment) |
| Last Date to Apply | 31 August 2026 |
Key Responsibilities
- Formulation Design: Develop lipid-based nanoparticle strategies, balancing mechanical robustness for storage with ultrasound-triggered release capabilities.
- Molecular Modeling: Utilize Coarse-Grained Molecular Dynamics (CGMD) to simulate nanoparticle properties and ultrasound-triggered release mechanisms.
- Empirical Validation: Conduct in vitro and in vivo studies to validate computational models, including the use of tumor-on-a-chip platforms.
- Collaboration: Work within the interdisciplinary SPARC consortium and alongside industrial partners such as Merck KGaA and Johnson & Johnson.
Eligibility & Qualifications
- Education: MSc or equivalent in Chemical Engineering, Pharmaceutical Sciences, Physical Chemistry, Biomedical Engineering, Nanotechnology, or a related field.
- Skills: Strong analytical mindset; ability to work across both computational and experimental domains.
- Communication: Excellent English proficiency.
- Preferred Experience: Prior experience with lipid-based nanoparticle formulations or coarse-grained molecular dynamic simulations is a plus.
How to Apply
Interested candidates should apply online via the TU Delft careers portal no later than 31 August 2026. Please include the following documents in your application:
- A detailed Curriculum Vitae (CV).
- Bachelor’s and Master’s transcripts (grade reports).
- A cover letter outlining your motivation and key experience.
Applications should be addressed to Dr. Alina Rwei. Early applications are encouraged, as the position has a flexible start date between Fall 2026 and February 2027.
