PhD Position in Single-Molecule Microfluidics: The University of Graz is offering a PhD position within the Molecular Biophysics Group focused on developing a single-molecule microfluidic assay for cancer diagnostics. This project aims to detect and quantify HER2 biomarker levels in solid tumors, incorporating innovative nanodisc technology and advanced experimental techniques.
PhD Position in Single-Molecule Microfluidics for Cancer Diagnostics
Designation
PhD Candidate
Research Area
- Chemistry
- Biochemistry
- Physics
- Biophysics
- Biological Engineering
Location
Institute of Molecular Biosciences (IMB), University of Graz, Austria
Address: Humboldtstraße 50, 8010 Graz, Austria
Eligibility/Qualification
- Applicants should hold (or be close to completing) a Master’s degree in:
- Biochemistry
- Bioengineering
- Biophysics
- Related fields
- Preferred qualifications include experience in:
- Assay development
- Cell biology
- Nanodisc technology
- Single-molecule fluorescence techniques
- Microfluidics
- Candidates should demonstrate motivation, capability for independent work, and a willingness to engage in interdisciplinary collaborations.
Job Description
The successful candidate will:
- Develop a single-molecule microfluidic assay for cancer diagnostics focusing on detecting HER2 levels.
- Work with native membrane-protein libraries using nanodisc-forming polymers.
- Design and fabricate microfluidic devices.
- Integrate fluorescence-based single-molecule detection techniques into an efficient assay workflow.
- Perform quantitative data analysis in a collaborative environment with Dr. Georg Krainer and Prof. Sandro Keller.
How to Apply
Interested candidates should submit a single PDF file containing:
- A cover letter outlining research interests, relevant expertise, and motivation for joining the project.
- A detailed CV including academic achievements and relevant research experience.
- Contact information for 2–3 references.
Applications should be sent to Dr. Georg Krainer at georg.krainer@uni-graz.at. The review of applications will begin immediately and continue until the position is filled.
Last Date to Apply

8 May 2025 – 00:00 (Europe/Brussels)
For more information, visit the Institute of Molecular Biosciences.