PhD Position in Stem Cells: The Department of Biomedical Sciences at the University of Lausanne, Switzerland, invites applications for a PhD position to explore partial reprogramming as a strategy to rejuvenate hematopoietic stem cells in aging and bone marrow failure syndromes. This project is offered by Dr. Gabriela Desdin-Micé’s junior research group in collaboration with Prof. Olaia Naveiras at Lausanne University Hospital (CHUV).
PhD Position in Rejuvenating Hematopoietic Stem Cells through Partial In Vivo Reprogramming
Designation: PhD Candidate
Research Area: Hematopoietic Stem Cell Rejuvenation, Aging, Bone Marrow Failure Syndromes
Location: Department of Biomedical Sciences, University of Lausanne, Switzerland
Eligibility/Qualification:
- Must meet requirements for the UNIL PhD Program in Cancer and Immunology.
- Experience in wet lab techniques (cell culture, flow cytometry, PCR).
- Experience in in vivo mouse research.
- Prior experience in bioinformatics (single-cell RNA analysis is a plus).
- Excellent communication skills in English.
- Independent, reliable, and collaborative-minded team player.
- Preferred candidates can start on January 1, 2025.
Job Description:
The successful candidate will work on a research project investigating the rejuvenation of hematopoietic stem cells through partial in vivo reprogramming. This project will utilize techniques such as bone marrow competitive transplantation, long-term ex vivo culture, and single-cell RNA sequencing of aged hematopoietic stem cells. The work will also involve the study of hIPS-derived hematopoietic progenitors from bone marrow failure syndromes such as Fanconi anemia and Shwachman-Diamond syndrome. The candidate will be co-supervised by Prof. Olaia Naveiras, an expert in the metabolic regulation of hematopoietic stem cell function.
How to Apply:
Applicants should submit a CV, transcript of records, and a letter of motivation addressing their talents, previous experiences relevant to the project, and reasons for pursuing a PhD. Applications should be sent to Dr. Gabriela Desdin-Micé at gabriela.desdin@unil.ch by October 28, 2024. Selected candidates will be invited for a laboratory visit and interview on November 7, 2024, which can be conducted online if needed.
Last Date to Apply: October 28, 2024
