PhD Position in Stochastic Modeling: The Inria Saclay-Île-de-France Research Centre invites applications for a PhD position focused on the stochastic modeling of plasmid copy number fluctuations in single cells. This position is a part of the ERC Starting Grant project led by Jakob Ruess and aims to develop mathematical models and statistical methods that will enhance our understanding of biochemical processes in single-cell dynamics and microbial populations.
PhD Position in Stochastic Modeling of Single-Cell Plasmid Copy Number Fluctuations
Designation
PhD Candidate (Doctorant)
Research Area
- Stochastic modeling
- Mathematical biology
- Statistics
- Control engineering
- Biochemical processes
Location
Inria Saclay-Île-de-France, Palaiseau, France
Eligibility/Qualification
- A degree in a theoretical field such as mathematics, physics, computer science, or control engineering, or a related discipline.
- Capability to apply methods from the aforementioned fields to study dynamical systems and stochastic processes.
- Familiarity with continuous-time Markov chains, stochastic differential equations, or stochastic chemical kinetics is advantageous but not essential.
- Candidates should be willing to deepen their understanding of biological applications throughout the project.
- Recent graduates or those expected to finish their studies soon are encouraged to apply.
Job Description
The PhD role will involve:
- Developing stochastic models of plasmid copy number fluctuations within single cells.
- Coupling these models to the dynamics of growing populations and microbial consortia.
- Applying statistical methods to infer model parameters from experimental data.
- Collaborating with biologists to implement modeling approaches on real data.
- Contributing to the overarching goal of designing synthetic gene circuits using mathematical modeling and control engineering.
How to Apply
Interested candidates must submit an online application through the Inria website, including:
- Curriculum Vitae (CV)
- List of publications (if applicable)
- Contact details of referees who can recommend the candidate
Last Date for Application
August 31, 2025
This position offers an exciting opportunity to engage in pioneering research at the intersection of multiple disciplines while contributing to significant advancements in synthetic biology.
