PhD Positions in Enzyme Evolution: The University of Groningen, specifically the Molecular Evolution group led by Prof. Clemens Mayer at the Stratingh Institute for Chemistry, is seeking two highly motivated PhD candidates. These positions, funded through an ERC Consolidator Grant, aim to address challenges related to the application of biocatalysts for synthetically-useful transformations. The focus is on continuous enzyme evolution, exploring rapid mutation, selection, and amplification cycles within living cells.
PhD Positions in Continuous Enzyme Evolution (2.0 FTE) (V24.0013)
Designation: PhD Candidate
Research Area: Continuous Enzyme Evolution
Location: Stratingh Institute for Chemistry, University of Groningen, Netherlands
Eligibility/Qualification:
- MSc degree in (Bio)chemistry / Biotechnology or a related field.
- Experience in directed evolution, bioinformatics, next-generation sequencing, bioreactor design/application, or synthetic chemistry is a plus.
- Interest in working at the interface of chemistry and synthetic biology.
- Ability to work independently.
Job Description: As a PhD candidate, you will:
- Engineer enzymes at an unprecedented rate and scale using continuous evolution approaches.
- Construct, automate, and apply a continuous evolution platform to engineer enzymes for C-C, C-halogen, or C-N bond-forming reactions.
- Utilize third-generation sequencing techniques and bioinformatics tools to map sequence-structure-function relationships of biocatalysts.
Conditions of Employment:
- Salary ranging from €2,770 to €3,539 gross per month based on a full-time position.
- Four-year position with the option of renewal for another three years.
- University PhD training program enrollment in the Graduate School of Science and Engineering.
- Preferred starting date between 01-05-2024 and 01-08-2024.
How to Apply: If you meet the qualification criteria, please upload the following documents:
- Letter stating your motivation and key qualities relevant to the position.
- Up-to-date curriculum vitae.
- Diplomas (BSc and MSc) and transcript of records.
- Contact information of two academic references.
Last Date for Apply: Applications are accepted until 11 February 2024, 11:59 pm (Dutch local time) / before February 12th, 2024. Apply through the electronic application form on the university website.
The University of Groningen is committed to inclusion and equality. We encourage applicants from underrepresented groups to apply. For more information, visit our diversity policy webpage.
Our selection procedure follows the guidelines of the Recruitment code (NVP) and the European Commission’s European Code of Conduct for recruitment of researchers.
For more information, contact Prof. Clemens Mayer at c.mayer@rug.nl.
