Summary
The Biomembrane Remodelling Group at Charles University is offering a PhD scholarship in the field of biomedical research, focusing on innovative drug-delivery systems targeting mitochondria. This opportunity is meant for motivated individuals interested in the theoretical and practical aspects of drug delivery mechanisms.
PhD Scholarship Opportunity: New Methods for Drug Delivery to Mitochondria
Designation
PhD Student in Drug Delivery Systems
Research Area
- Computational Materials Science
- Molecular Biophysics
- Life Sciences
Location
Prague, Czech Republic
Eligibility/Qualification
- Passion for biological mechanisms, membrane biophysics, and mathematical modeling, particularly Helfrich curvature elasticity theory.
- Strong programming skills in Python or C++.
- Interest in molecular dynamics simulations; prior experience is advantageous (especially with enhanced sampling or GROMACS knowledge).
- Experience in finite element computational modeling is a plus.
Job Description
| Key Responsibilities |
|---|
| Leverage unique toolkit to extract membrane properties from molecular dynamics simulations and predict remodeling. |
| Develop and optimize a mitochondria-targeted drug platform focusing on endosomal escape using advanced simulations. |
| Explore mitochondrial morphology and membrane remodeling proteins’ influence on ultrastructure. |
| Test hypotheses with synthesized compounds, cryoelectron microscopy, and fluorescence imaging through collaborations. |
How to Apply
Interested applicants should send a cover letter and CV with references to Christoph Allolio at allolio@karlin.mff.cuni.cz.
Last Date to Apply
August 12, 2026
Explore the opportunity to enhance your career while contributing to cutting-edge research in drug delivery systems!
