Summary:
Join our research team at Radboud University Medical Center as a PhD candidate focusing on enhancing the interpretation of gene variants through innovative transactivation methods and functional readouts. This is an excellent opportunity for those interested in genomics and rare diseases.
PhD Candidate Scholarship in Improving Gene Variant Interpretation, Radboud University Medical Center, Nijmegen, Netherlands
Designation: PhD Candidate
Research Area:
- Genomics
- Rare Diseases
- Molecular Biology
- Genetic Disorders
Location:
Radboud University Medical Center, Nijmegen, Netherlands
Eligibility/Qualification:
- Master’s degree in Molecular Biology, Genetics, Medical Biology, Biomedical Sciences, or a related discipline.
- Strong interest in biology, genomics, and rare diseases.
- Desirable experience in molecular biology.
Job Description:
| Task | Details |
|---|---|
| Identify eligible variants | Analyze historic databases for variants. |
| Gene activation | Create CASP9-based constructs for gene activation and transduction. |
| Transcript analysis | Conduct transcript and transcriptome analyses of transduced cells. |
| Functional readouts | Perform immunohistochemistry, western blotting, and enzymatic tests. |
| Communication | Present findings at local and international scientific meetings; write scientific papers. |
| Collaboration | Work in an interdisciplinary team with clinicians, bioinformaticians, and molecular biologists. |
| Dissertation | Complete the project with a scientific dissertation. |
How to Apply:
Interested candidates should fill out the application form on the Radboudumc careers page, including their CV and cover letter.
Last Date to Apply:
May 1, 2026
Take the next step in your academic career and contribute to groundbreaking research at Radboudumc!
