Summary
A fully funded 36-month PhD scholarship is available at the Coordination Chemistry Laboratory (CNRS), Toulouse, France, focusing on innovative therapeutic strategies for Alzheimer’s disease. This interdisciplinary project explores the development of traceable copper ligands to target disease mechanisms at the interface of chemistry and biology. The position is funded by the Vaincre Alzheimer Foundation and begins on 1st July 2026.
Designation
PhD Research Scholar (Doctoral Candidate)
Research Area
- Bioinorganic Chemistry
- Alzheimer’s Disease Research
- Therapeutic Chemistry
- Molecular & Cellular Biology
- Neurochemistry
Location
- Coordination Chemistry Laboratory (LCC), CNRS – Toulouse, France
- Institute of Cellular and Integrative Neurosciences – Strasbourg, France
Eligibility / Qualification
Candidates must have:
- A Master’s degree (or equivalent) in:
- Cellular Biology
- Molecular Biology
- Biochemistry
- Pharmacology
- Or related disciplines
- Strong interest in:
- Chemistry–biology interface
- Therapeutic research
- Personal qualities:
- Motivation and perseverance
- Ability to work in a multidisciplinary research environment
Job Description
The selected candidate will work on a cutting-edge project titled:
“Evaluation of New Traceable Copper Ligands as a Therapeutic Approach to Alzheimer’s Disease.”
Key responsibilities include:
- Testing novel copper-binding ligands (L) developed at LCC
- Studying their ability to:
- Remove copper from Cu-Aβ complexes
- Reduce reactive oxygen species (ROS) production
- Prevent toxic amyloid aggregation
- Conducting:
- In vitro experiments (test tube studies)
- Cell-based studies using model cell lines
- Investigating:
- Cellular uptake of ligands
- Copper distribution in cells
- Effects on cell viability and inflammation markers
- Using advanced techniques such as:
- Time-resolved confocal microscopy
- Collaborating across two research institutes under expert supervision
Funding / Salary
- Fully funded PhD position (36 months)
- Sponsored by the Vaincre Alzheimer Foundation.
How to Apply
Applicants must submit:
- 📄 Updated CV (including academic history)
- ✉️ Cover Letter
- 📊 Latest academic transcripts/results
- 📞 Two references
📧 Contact for Application:
Charlène Esmieu
Email: charlene.esmieu@lcc-toulouse.fr
Phone: +33 5 61 33 31 20
Last Date to Apply
- Open Now (Apply as early as possible before the start date: 1st July 2026)
