PhD Student in Pediatric Brain Tumors: Join the German Cancer Research Center’s Division of Pediatric Neurooncology as a PhD student to investigate the role of recurrent copy-number alterations (CNAs) in pediatric brain tumors. Utilize cutting-edge mouse models and bioinformatic analyses to advance cancer research and contribute to significant findings in tumor evolution.
PhD Student in CNV-Mediated Evolution of Pediatric Brain Tumors
Designation
PhD Student – CNV-Mediated Evolution of Pediatric Brain Tumors
| Details | Information |
|---|---|
| Research Area | Pediatric Neurooncology |
| Location | Heidelberg, Germany |
| Eligibility/Qualification | Completed master’s or diploma in biology, bioinformatics, or related field |
| Application Deadline | 16.09.2025 |
Research Area
The focus is on the study of recurrent copy-number alterations (CNAs) in high-grade glioma and medulloblastoma, using somatic mouse models to mimic patient tumors and analyze their role in tumorigenesis.
Eligibility/Qualification
- Completed master’s or diploma degree in biology, bioinformatics, or a related field.
- Knowledge of tumor biology, especially brain tumors; experience in bioinformatics is advantageous.
- Proficiency in Linux/Unix command line and R; knowledge of programming languages is preferred.
- Excellent communication skills and attention to detail.
Description
The PhD student will:
- Establish the timing of CNAs in tumor progression.
- Analyze gene expression and chromatin accessibility over time using single-cell RNA and ATAC sequencing.
- Identify occurrences of CNAs at a genomic level.
- Examine clonality and gene expression changes to determine functional impacts of early CNAs using single-cell whole-genome sequencing.
- Collaborate with peers and work independently within a supportive environment.
How to Apply
Interested candidates should apply through the specified portal. Applications through email will not be accepted, and mailed applications will not be returned.
Last Date to Apply
16th September 2025
Join us in our mission “Research for a life without cancer” and contribute to pioneering cancer research!
