PhD Student Position: Biochemistry/Molecular Toxicology, University of Basel, Switzerland

PhD Fellowship IN Switzerland

PhD Student Position: Biochemistry: The University of Basel’s Division of Molecular and Systems Toxicology is inviting applications for a PhD student position in Biochemistry/Molecular Toxicology. The position involves investigating substances altering corticosteroid hormone action, contributing to a collaborative project financed by the Swiss Centre for Applied Human Toxicology.

PhD Student Position: Biochemistry/Molecular Toxicology

Designation: PhD Student
Research Area: Biochemistry/Molecular Toxicology
Location: University of Basel, Switzerland
Eligibility/Qualification: MSc in the field of Life Sciences, basic experience in biochemistry/molecular biology methods, and cell culture.

Job Description:

The successful candidate will be part of a collaborative effort with four other partners to study chemical-induced steroid perturbations. Key responsibilities include:

  1. Establishing and applying methods and cell-based assays to assess chemical-induced alterations in glucocorticoid pre-receptor enzyme activity and regulation.
  2. Generating promoter-reporter cell lines for HSD11B1 and HSD11B2 and conducting enzyme activity assays.
  3. Constructing stable cell lines expressing promoter-reporter constructs or glucocorticoid receptor (GR) reporter plasmids.
  4. Investigating compounds such as PFAS, phthalates, bisphenols, UV-filters, and parabens for direct inhibitory activity using established assays.
  5. Utilizing cell culture, transfection, gene expression analyses, molecular cloning, receptor function analyses, and enzyme activity measurements.

Your Profile:

  • MSc in the field of Life Sciences.
  • Basic experience in biochemistry/molecular biology methods and cell culture.
  • Fluent communication in English, both written and oral.
  • Highly motivated, interactive team player.

We Offer You:

  • PhD student position with a timeframe of 4 years to achieve the PhD.
  • Training in key techniques.
  • International research environment.
  • Participation in the PhD program Pharmaceutical Sciences.
  • Integration into the Swiss Centre of Applied Human Toxicology network.

How to Apply:

Applications must include a full CV, a short motivation letter, copies of degrees and qualifications, and the names/contact data of at least two referees. General inquiries can be directed to Please submit applications exclusively through our online application portal. Applications via email, postal services, or agencies will not be considered.

Last Date for Apply: Until position filled

Disclaimer: This job post is sourced from a reliable channel. Please verify details from the official University of Basel website for additional information and updates.



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