PhD Student Position: Nanoscale: The HOLTHUIS LAB is inviting applications for a PhD student to join the DFG-funded Research Training Group RTG-2900 “nanomaterials@biomembranes”. The project focuses on the controlled permeabilization of cells to facilitate the delivery of synthetic peptides and other biomolecules. This interdisciplinary research combines nanotechnology and super-resolution live cell imaging to study how cells respond to membrane disruption and repair.
PhD Student Position in Interrogating Plasma Membrane Permeabilization and Repair at Nanoscale
Summary Table
| Position | PhD Student (f/m/d) |
|---|---|
| Project Title | Interrogating Plasma Membrane Permeabilization and Repair at Nanoscale |
| Application Deadline | June 15, 2024 |
| Start Date | As soon as possible |
| Duration | 3 years |
| Salary | E13/65% level according to the German TV-L scale |
| Location | University of Osnabrück, Germany |
Study Area
- Lipid cell biology
- Nanotechnology
- Super-resolution live cell imaging
Scholarship Description
The successful candidate will work on developing novel strategies for cytosolic delivery of polar therapeutics and understanding how cells repair minor membrane lesions. The project will involve combining supramolecular materials with live cell imaging to study cargo transport and membrane repair-associated lipid scrambling.
Key References:
- Barba-Bon et al., 2022, Nature 603, 637-642
- Niekamp et al., 2022, Nature Comm 13, 1875
- Sokoya et al., 2022, eLife 11, e79278
- Holthuis & Menon, 2014, Nature 510, 48-57
Eligibility
- Completed degree (M.Sc.) in biology, (bio)chemistry, or biophysics
- Solid background in assay development, ideally with expertise in live cell microscopy
- Strong interest in interdisciplinary research
- Ability to work in a team and willingness to engage in multilateral research cooperation
- Very good command of written and spoken English
Required Documents
- Informative letter of motivation
- Curriculum vitae with a list of publications
- Names and contact details of two academic referees
How to Apply
Applications should be sent as a single PDF document by June 15, 2024 to Prof. Dr. Joost Holthuis (holthuis@uos.de). For further information, contact Prof. Dr. Joost Holthuis (holthuis@uos.de; Phone +49 541 969 7140).
Last Date
The application deadline is June 15, 2024.








