PhD Student Position – Site Recognition: The Institute for Molecular Infection Biology (IMIB) at Julius-Maximilians-Universität Würzburg, Germany, invites applications for a PhD Student position in the Beusch Group. This interdisciplinary PhD project focuses on understanding the early steps of spliceosome assembly and RNA splicing regulation, combining forward genetics, biochemistry, molecular biology, and RNA-sequencing approaches. The position offers an inclusive, international research environment with strong mentoring and opportunities for scientific growth.
PhD Student Position (f/m/d) – Regulation of Early Spliceosome Assembly and Splice Site Recognition
Summary Table
| Item | Details |
|---|---|
| Institution | Julius-Maximilians-Universität Würzburg |
| Institute | Institute for Molecular Infection Biology (IMIB) |
| Research Group | Beusch Group |
| Position | PhD Student (f/m/d) |
| Employment Type | Part-time (65%) |
| Contract Duration | 1 year (extendable based on progress) |
| Salary | TV-L (German public sector pay scale) |
| Location | Würzburg, Germany |
| Application Deadline | March 08, 2026 |
Designation
PhD Student (f/m/d)
Research Area
- RNA Biology
- RNA Splicing and Spliceosome Assembly
- Post-transcriptional Gene Regulation
- Molecular Biology and Biochemistry
- Functional Genomics and RNA-seq
Location
Institute for Molecular Infection Biology (IMIB)
Julius-Maximilians-Universität Würzburg
Würzburg, Germany
Eligibility / Qualification
Applicants should meet the following criteria:
- Master’s degree in Life Sciences (e.g., Molecular Biology, Biochemistry, Biotechnology, or related fields)
- Strong background or interest in RNA biology or biochemistry
- Experience in molecular biology techniques, tissue culture, cell line engineering, RNA-seq analysis, or bioinformatics is advantageous but not mandatory
- Strong written and spoken English communication skills
- Motivation to work independently and collaboratively in an international research environment
- Willingness to learn advanced experimental and analytical techniques
Job Description
The successful candidate will work on an interdisciplinary research project investigating regulation during the earliest stages of spliceosome assembly. The project aims to uncover how splice site recognition occurs and how it integrates with the dynamic assembly of the spliceosome, a complex molecular machine composed of more than 150 proteins and multiple small nuclear RNAs.
The PhD student will:
- Study molecular mechanisms governing spliceosome assembly and splice site choice
- Apply RNA-seq–based approaches, molecular biology, and biochemical methods
- Use advanced techniques such as proximity labeling, immunoprecipitation-mass spectrometry (IP-MS), and forward genetics
- Contribute to fundamental understanding of eukaryotic gene regulation and disease-related splicing defects
How to Apply
Interested candidates should submit their application as a single PDF file including:
- Letter of motivation
- Curriculum vitae with research experience
- Contact details of two academic references
Email applications to:
📧 irene.beusch@uni-wuerzburg.de
Email subject: PhD position AG Beusch
For informal inquiries, please contact:
Dr. Irene Beusch
Institute for Molecular Infection Biology
Julius-Maximilians-Universität Würzburg
Email: irene.beusch@uni-wuerzburg.de
Website: www.beuschlab.org
Last Date for Apply
🗓 March 08, 2026
