Postdoc Position in Biological and Medicinal Chemistry at ETH Zurich, Switzerland

Postdoc Position at University of Zurich Switzerland

Postdoc Position in Biological and Medicinal Chemistry: Join the ETH Laboratory of Toxicology at ETH Zurich, led by Professor Shana Sturla. We are a multidisciplinary team at the chemistry-biology interface, exploring the relationship between chemical structures, biomolecular processes, and cellular responses relevant to chemical safety and drug development. We have a postdoctoral opportunity focusing on chemical biology/medicinal chemistry of nucleic acid-protein interactions. The research includes small molecule synthesis, modified oligonucleotides, protein interactions related to DNA repair in cancer cells, covalent inhibition, and the development of precision cancer therapeutics. High throughput drug screens and in vitro toxicity evaluation may be part of the research. Join us in advancing biological and medicinal chemistry.

Designation: Postdoctoral Researcher

Research Area: Biological and Medicinal Chemistry

Location: ETH Zurich, Department of Health Science & Technology, Switzerland

Eligibility/Qualification:

  • PhD or equivalent in chemistry, medicinal chemistry, or a related discipline.
  • Proficiency in organic synthesis of small molecules.
  • Excellent written and oral communication skills in English.
  • Independent, flexible, and motivated to work in an international and team-oriented environment.

Job Description:

Postdoc Position in Biological and Medicinal Chemistry

As a Postdoc in Biological and Medicinal Chemistry, your research will involve:

  • Synthesis of small molecules and modified oligonucleotides.
  • Evaluation of interactions with proteins related to DNA repair in cancer cells.
  • Covalent inhibition studies.
  • Contribution to the development of precision cancer therapeutics.
  • Possible involvement in high throughput drug screens and in vitro toxicity evaluations.
  • Collaborative research opportunities in environmental toxicants, DNA damage, mutagenesis, and microbial metabolism of chemicals.

The initial contract is for 1 year, with the possibility of extension up to 6 years, depending on funding availability.

How to Apply: Interested candidates should send the following to ethtoxrec@hest.ethz.ch:

  • A brief email describing research experience and scientific/professional goals.
  • CV including publication list and contact information for 3 referees (do not include letters of recommendation).

Applications will be considered on an ongoing basis until the position is filled.

For inquiries, contact Prof. Shana Sturla at sturlas@ethz.ch.

Last Date for Apply: Applications accepted until the position is filled.

Salary: Salary details available upon inquiry. Join ETH Zurich, a world-leading university in science and technology, and contribute to groundbreaking research in biological and medicinal chemistry.

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