Postdoctoral Fellow – Jones Lab: The Personalized Approaches in the Treatment of Head and Neck Cancer (PATH) study seeks a highly motivated postdoctoral fellow to lead the development of an integrated analysis pipeline for detecting minimal residual disease (MRD) in head and neck cancer patients through longitudinal plasma cell-free DNA sequencing.
Designation
Postdoctoral Fellow
Job Details
| Category | Details |
|---|---|
| Research Area | Bioinformatics, Computational Biology |
| Location | Vancouver, British Columbia, Canada |
| Salary Range | $50,000 – $70,000 per annum |
| Job Type | Temporary Full-Time, Hybrid |
Eligibility/Qualification
- Ph.D. in Bioinformatics, Computational Biology, Genomics, Computer Science, or a related discipline.
- Expertise in next-generation sequencing data analysis (Illumina and ONT platforms).
- Strong programming skills (Python, R, C/C++ or similar).
- Proficiency with workflow management tools (Snakemake, Nextflow, CWL) and version control (Git).
- Excellent communication and interpersonal skills.
- Proven publication record in cancer genomics or related fields.
Job Description
The postdoctoral fellow will:
- Design and implement an analysis pipeline to detect low tumor fractions from plasma ctDNA using genomic data.
- Adapt and evaluate existing tools and develop novel algorithms to enhance MRD sensitivity and specificity.
- Perform longitudinal analyses of plasma samples, tracking ctDNA tumor fraction over time.
- Conduct tumor-informed analysis leveraging matched tumor and normal WGS data.
- Generate comprehensive reports, visualizations, and manuscripts for internal review and publications.
How to Apply
Interested candidates should submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca using Job Reference No. PDF_01553_Jones Lab_ctDNA MRD_2026_01_30 in the subject line.
Last Date for Apply
This posting will remain online until the position is filled. However, applications are encouraged as soon as possible.
Note: Preference will be given to Canadian citizens and permanent residents.
