Postdoctoral in Mechanisms of Cell Signalling: The Ranes lab at the University of Oxford is seeking a talented Postdoctoral Research Associate to investigate the molecular mechanisms driving the Wnt/beta-catenin signalling pathway. This position offers an exciting opportunity to engage in multidisciplinary research using cutting-edge techniques in biochemistry, biophysics, cell biology, and structural biology.
Postdoctoral Research Associate in Mechanisms of Cell Signalling
Designation
Postdoctoral Research Associate
Research Area
Mechanisms of Cell Signalling, with a focus on the Wnt/beta-catenin signalling pathway
Location
Department of Biochemistry, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU, UK
Eligibility/Qualification
- A PhD/DPhil or near completion in Biochemistry, Cell Biology, or a related discipline.
- Substantial experience in basic molecular biology techniques, particularly recombinant DNA techniques.
- Proficiency in expression and purification of recombinant proteins.
- Experience in biochemical and biophysical characterisation methods.
- Knowledge and skills in mammalian cell culture and associated cell-based techniques.
- Strong organizational skills with the ability to prioritize and multitask.
- Excellent oral and written communication skills, suitable for publication and presentation.
Job Description
The successful candidate will:
- Investigate the mechanisms of Wnt pathway activation and termination at the plasma membrane.
- Utilize state-of-the-art tools such as in vitro protein reconstitution, CRISPR approaches, and super-resolution microscopy.
- Study the regulation and recruitment of cytoplasmic signal transduction proteins to Wnt receptor complexes.
- Work independently and collaboratively within the lab, contributing to innovative research ideas and findings.
How to Apply
Applications must be made online via www.recruit.ox.ac.uk with Vacancy ID 179455. Applicants are required to upload:
- A curriculum vitae (CV)
- A supporting statement addressing how they meet the selection criteria, including relevant examples.
- Details of two referees (indicating whether they can be contacted now).
For further inquiries, contact recruitment@bioch.ox.ac.uk.
Last Date for Apply
The closing date for applications is 12.00 noon on Monday, 2nd June 2025. Only applications received before this time will be considered. Interviews for shortlisted candidates will be conducted as soon as possible thereafter.
