Postdoctoral in Mechanisms of Cell Signalling: The Ranes lab at the Department of Biochemistry, University of Oxford, is seeking a talented and motivated Postdoctoral Research Associate to explore the molecular mechanisms driving the Wnt/beta-catenin signalling pathway.
Postdoctoral Research Associate in Mechanisms of Cell Signalling
Designation
Postdoctoral Research Associate
Table
| Details | Information |
|---|---|
| Pay Scale | STANDARD RESEARCH GRADE 7 |
| Salary (£) | £41,997 – £46,913 per annum |
| Location | Department of Biochemistry, South Parks Road, Oxford |
| Contract Type | Fixed Term Contract for up to 3 years |
| Hours | Full Time (37.5 hours per week) |
| Closing Date for Applications | 12.00 noon on Monday, 2nd June 2025 |
Research Area
Molecular mechanisms of cell signalling, specifically focusing on the Wnt/beta-catenin signalling pathway.
Location
Dorothy Crowfoot Hodgkin Building, Department of Biochemistry, South Parks Road, Oxford, OX1 3QU, United Kingdom.
Eligibility/Qualification
- PhD/DPhil in Biochemistry, Cell Biology or related discipline (or near completion).
- Substantial experience in molecular biology techniques, especially recombinant DNA techniques.
- Proven experience in protein expression and purification.
- Proficiency in biochemical and biophysical characterization methods is essential.
- Knowledge in mammalian cell culture and associated techniques.
- Strong organisational skills, capable of multitasking independently and within a team.
- Excellent oral and written communication skills, with the ability to publish and present research findings.
Job Description
The Postdoctoral Research Associate will investigate the activation and termination mechanisms of the Wnt pathway at the plasma membrane, utilizing both in vitro and cell-based approaches. Responsibilities include:
- Studying the regulation of cytoplasmic signal transduction protein recruitment to Wnt receptor complexes.
- Employing state-of-the-art tools such as in vitro protein reconstitution, CRISPR approaches, and super-resolution microscopy.
- Collaborating within a multidisciplinary lab environment that integrates biochemistry, biophysics, cell biology, and structural biology.
How to Apply
Interested candidates should submit their application online via www.recruit.ox.ac.uk with Vacancy ID 179455. Applicants are required to upload:
- Curriculum Vitae
- Supporting statement detailing how they meet the selection criteria.
- Details of two referees, indicating availability for contact.
For further queries, please contact recruitment@bioch.ox.ac.uk.
Last Date for Apply
Applications must be submitted by 12.00 noon on Monday, 2nd June 2025. Only applications received before this time will be considered. Interviews for shortlisted candidates will be conducted as soon as possible thereafter.
