Postdoctoral in Mechanisms of Cell Signalling: The Department of Biochemistry at the University of Oxford invites applications for a highly motivated and talented Postdoctoral Research Associate to join the Ranes Lab. The successful candidate will explore the molecular mechanisms of Wnt/β-catenin signal transduction, using multidisciplinary approaches involving biochemistry, structural biology, and cell biology. This role is funded by the Wellcome Trust and presents an outstanding opportunity to work in a world-class research environment.
Postdoctoral Research Associate in Mechanisms of Cell Signalling
Job Summary Table:
| Field | Details |
|---|---|
| Position | Postdoctoral Research Associate |
| Division | Medical Sciences Division |
| Department | Department of Biochemistry |
| Location | New Biochemistry Building, South Parks Road, Oxford, OX1 3QU |
| Grade/Salary | Grade 7: £41,997 – £46,913 per annum |
| Hours | Full-time (37.5 hours/week) |
| Contract Type | Fixed-term (3 years initially, possible extension) |
| Principal Investigator | Dr Michael Ranes |
| Vacancy Reference | 179455 |
| Funding Source | Wellcome Trust |
| Lab Website | Ranes Lab |
| Application Portal | University Jobs Site |
| Application Deadline | Midday UK time on the date specified in the online ad |
Designation:
Postdoctoral Research Associate
Research Area:
Mechanisms of Cell Signalling – Wnt/β-catenin pathway
Location:
Department of Biochemistry, New Biochemistry Building, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK
Eligibility/Qualifications:
Essential:
- PhD/DPhil (or near completion) in Biochemistry, Cell Biology, or related field.
- Expertise in molecular biology techniques (especially recombinant DNA).
- Experience with recombinant protein expression and purification.
- Strong skills in mammalian cell culture, microscopy, and cell-based assays.
- Proven track record of peer-reviewed publications (at least one first-author paper).
- Excellent communication, organisational, and teamworking skills.
Desirable:
- Experience with membrane proteins.
- Proficiency in super-resolution imaging and CRISPR gene editing.
Job Description:
You will work independently and collaboratively to:
- Investigate Wnt receptor complex signalling mechanisms at the plasma membrane.
- Conduct protein biochemistry, CRISPR-based manipulation, and microscopy experiments.
- Design and perform cell-based and in vitro biochemical assays.
- Maintain detailed records, publish findings, and present at conferences.
- Contribute to mentoring junior lab members and managing daily lab operations.
You will benefit from a collaborative lab environment and strong institutional support for career and personal development.
How to Apply:
Apply through the University of Oxford’s recruitment portal:
👉 https://www.jobs.ox.ac.uk/how-to-apply
Required documents:
- CV
- Supporting Statement (detailing how you meet the selection criteria)
- Contact information for three referees
Note: Your application will not be considered without both the CV and supporting statement.
Last Date to Apply:
Until position filled
For queries, email: 📧 recruitment@bioch.ox.ac.uk
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