Postdoctoral in Molecular Genetics & Synthetic Biology: The Hsiung Lab at the University of California, San Francisco (UCSF) is seeking highly motivated and exceptionally capable Postdoctoral Researchers to join an innovative research program at the intersection of molecular genetics, synthetic biology, and functional genomics. The lab recently developed a cutting-edge functional genomics platform leveraging engineered CRISPR-Cas12a to explore higher-order combinatorial genetic perturbations (Hsiung et al., Nature Biotechnology, 2024). Successful candidates will work on pioneering projects aimed at understanding and engineering emergent properties of genetic elements and tissues.
Postdoctoral Researcher in Molecular Genetics & Synthetic Biology
Summary Table
| Item | Details |
|---|---|
| Institution | University of California, San Francisco (UCSF) |
| Laboratory | Hsiung Lab |
| Position | Postdoctoral Researcher |
| Research Focus | Molecular Genetics, Synthetic Biology, Functional Genomics |
| Location | San Francisco, California, USA |
| Application Mode | |
| Contact | Chris Hsiung (Chris.Hsiung@ucsf.edu) |
Designation
Postdoctoral Researcher
Research Area
- CRISPR synthetic biology and functional genomics
- Enhancer biology and epigenetics
- Tissue injury responses (fibrosis and regeneration)
- Human tissue biology using surgical specimens
- Therapeutic cell reprogramming
- Genetic screens for emergent tissue properties
- Cell–cell interactions and spatially resolved genomics
- Engineering cancer cells for immune recognition
Location
University of California, San Francisco (UCSF)
San Francisco, California, USA
Eligibility / Qualification
- PhD in Molecular Biology, Genetics, Synthetic Biology, Genomics, Immunology, Computational Biology, or a closely related field
- Strong interest in CRISPR-based technologies and functional genomics
- Desirable experience in one or more of the following:
- Single-cell and/or spatial genomics
- Immunology or immuno-oncology
- Genome regulation
- Liver biology
- Computational biology
- Mouse models
- Ability to work independently as well as collaboratively in a multidisciplinary research environment
Job Description
- Develop and/or apply advanced CRISPR-based synthetic biology and functional genomics tools
- Conduct genetic screens to study emergent properties of tissues
- Investigate enhancer biology, epigenetics, and tissue injury responses
- Work with novel human tissue models derived from surgical specimens
- Collaborate with junior specialists and multidisciplinary teams within the lab
- Contribute to high-impact publications and presentations
How to Apply
Interested candidates should email the following documents to Chris Hsiung at Chris.Hsiung@ucsf.edu:
- Curriculum Vitae (CV)
- Statement of research interest and motivation to join the lab
- Potential start date
- Contact information for 2–3 professional references
Last Date for Apply
Rolling basis until the position is filled
