Postdoctoral Position: Anticancer Drug Resistance: The Truman Lab at UNC Charlotte, USA, invites applications for a postdoctoral position to explore the broad role of Hsp70 modifications in cancer, specifically focusing on anticancer drug resistance. The project will utilize various molecular technologies, including cross-linking mass spectrometry, CRISPR-genome engineering, and high-throughput screening in yeast and mammalian cells. The lab is funded by NIH for several years, and candidates are expected to collaborate with Dr. Truman to apply for fellowships during this period.
Designation: Postdoctoral Researcher
Research Area: Molecular Chaperones in Anticancer Drug Resistance
Location: UNC Charlotte, USA
Eligibility/Qualification:
- PhD in biochemistry, molecular biology, cancer biology, or a related field.
- Experience in basic molecular biology and biochemistry techniques.
- Experience in cell/tissue culture and cell-based assays.
- Expertise in chaperone biology, signal transduction, or neurodegenerative disease, evidenced by publications in high-impact journals.
Useful Qualifications:
- Experience generating new cell lines by CRISPR.
- Experience in protein cross-linking experiments.
- Experience in fluorescence microscopy and/or flow cytometry.
Job Description:
Postdoctoral Position: Role of Molecular Chaperones in Anticancer Drug Resistance
The selected candidate will work in the Truman Lab, focusing on understanding the molecular mechanisms underlying anticancer drug resistance. The project involves utilizing advanced molecular technologies, including cross-linking mass spectrometry and CRISPR-genome engineering, to investigate the role of Hsp70 modifications in cancer. The candidate is expected to contribute to high-impact publications and collaborate closely with Dr. Truman.
How to Apply: Interested candidates should email Dr. Truman at atrumanl@uncc.edu. The application must include a cover letter describing how previous experience aligns with the lab’s focus, a CV, and any relevant publications.
Last Date for Apply: Applications will be accepted until the position is filled. Ideal candidates are those who have graduated less than one year from their start date in the Truman Lab.
Table: Required Qualifications
| Qualifications | |
|---|---|
| PhD in biochemistry, molecular biology, cancer biology, or related field | |
| Experience in basic molecular biology and biochemistry techniques | |
| Experience in cell/tissue culture and cell-based assays | |
| Expertise in chaperone biology, signal transduction, or neurodegenerative disease | Evidenced by publications in high-impact journals |
Table: Useful Qualifications
| Qualifications | |
|---|---|
| Experience generating new cell lines by CRISPR | |
| Experience in protein cross-linking experiments | |
| Experience in fluorescence microscopy and/or flow cytometry |
Join the collaborative research environment at UNC Charlotte’s Department of Biological Sciences, led by Dr. Truman, as part of the Charlotte Group for Proteostasis Research (CGPR). The university offers a comprehensive benefits package and a competitive salary, while the Charlotte region provides an excellent environment to work and live.
