The Simonetti Lab at Johns Hopkins University is seeking a postdoctoral fellow interested in developing new therapeutic interventions to eliminate HIV-1 reservoirs.
Designation: Postdoctoral Fellow
Research Area: HIV-1 Cure Research
Location: Department of Medicine, Johns Hopkins University, Baltimore, MD
Eligibility/Qualification:
- Ph.D. in biology, virology, immunology, pharmacology, or related field
- Experience in primary cell culture, flow cytometry, and cell sorting
- Quantification of rare DNA or RNA targets from clinical samples
- Molecular biology, sequence analysis
- Programming (R, Python)
- Curiosity, creativity, and intrinsic motivation for research topic
- Excellent communication skills (non-native speakers are welcome)
- Willingness to interact with other members of the laboratory in a way that raises the scientific excellence of the whole group
Job Description: The postdoctoral fellow will work on a fully funded (RO1) project to determine the role of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in inducing CARDS-sensing of HIV-1 Protease activity and death of infected cells by pyroptosis. The postdoc will integrate assays ex vivo on primary cells from people with HIV-1, animal models, and samples from clinical trials. The postdoc will gain expertise on the entire spectrum of HIV-1/host interactions, from molecular virology to innate and adaptive immunity. The postdoc will coordinate studies between the lab and collaborators in the broader HIV cure community.
How to Apply: To apply, please send a single pdf containing all application materials (cover letter, curriculum vitae, name and contact information of three academic references) to fsimonetti@ihmi.edu.
Last Date for Apply: Applications will continue to be accepted and considered until the job position is filled.
Required and Desired Qualifications
| Required Qualifications | Desired Qualifications |
|---|---|
| Ph.D. in biology, virology, immunology, pharmacology, or related field | Experience in primary cell culture, flow cytometry, and cell sorting |
| Quantification of rare DNA or RNA targets from clinical samples | |
| Molecular biology, sequence analysis | |
| Programming (R, Python) | |
| Curiosity, creativity, and intrinsic motivation for research topic | |
| Excellent communication skills (non-native speakers are welcome) | |
| Willingness to interact with other members of the laboratory in a way that raises the scientific excellence of the whole group |
| Premature PR activation |
| Abundant one-on-one mentoring and training opportunities |
| Freedom and support to develop an independent research profile |
| Friendly, diverse, team-oriented work environment |
