Postdoctoral Position in Organic Synthesis: The ICOA – Institut de Chimie Organique et Analytique at Université d’Orléans is seeking a highly motivated and skilled postdoctoral researcher for a multi-step synthesis project in organic chemistry. The project focuses on the synthesis and bioconjugation of chondroitin sulfate oligosaccharides, which are complex polysaccharides involved in various biological processes.
| Title | Postdoctoral Position in Organic Synthesis |
|---|---|
| Location | ICOA, UMR-CNRS 7311, Université d’Orléans, BP 6759, rue de Chartres, 45067 Orléans Cedex 2 |
| Research Area | Organic Synthesis, Glycochemistry, Bioconjugation |
| Eligibility/Qualification | PhD in Organic Synthesis |
| Start Date | Autumn 2024 |
| Duration | 12 months (renewable once) |
| Funding | ANR MODULATE |
| Last Date to Apply | July 1st, 2024 |
Designation
Postdoctoral Researcher
Research Area
Organic Synthesis, Glycochemistry, Bioconjugation
Location
ICOA, UMR-CNRS 7311, Université d’Orléans, BP 6759, rue de Chartres, 45067 Orléans Cedex 2
Eligibility/Qualification
- PhD in Organic Synthesis
- Proficiency in synthesis, purification, and structural characterization
- Experience in glycochemistry and/or bioconjugation is a plus but not mandatory
- Interest in chemistry-biology interface topics
Job Description
The successful candidate will work on synthesizing and bioconjugating chondroitin sulfate (CS) oligosaccharides. CS are complex polysulfated polysaccharides involved in biological processes such as cartilage tissue homeostasis, cell adhesion, and neuronal growth. Due to their complex structure, synthesizing large CS oligosaccharides (> octasaccharides) is challenging.
Project Tasks Include:
- Synthesizing functionally diverse CS oligosaccharides with varying sizes and sulfation motifs.
- Exploring various bioconjugation methods for these oligosaccharides.
- Structural characterization and biological activity evaluation of the glycoconjugates in collaboration with Dr. Régis Daniel (LAMBE, Univ. Evry), Dr. Fabien Lecaille (CEPR, Tours), and GLYcoDiag (Orléans).
How to Apply
Applicants should submit the following documents in a single PDF file:
- Curriculum Vitae (CV)
- Brief summary of research activities
- Cover letter
- Contact details of two referees
Send the application to:
- Pr. Chrystel Lopin-Bon: chrystel.lopin-bon@univ-orleans.fr
- Dr. Marie Schuler: marie.schuler@univ-orleans.fr
Last Date for Apply
July 1st, 2024
