Summary
Uppsala University’s Department of Pharmacy is seeking a highly motivated Postdoctoral Researcher to join their interdisciplinary environment. This position focuses on developing platform approaches for pharmacokinetic-pharmacodynamic (PK-PD) modelling in oncology, contributing to advancements in cancer therapy development.
Designation
Postdoctoral Researcher
Research Area
- Pharmacokinetic-Pharmacodynamic (PK-PD) Modelling
- Pharmacometrics
- Oncology Drug Development
- Quantitative and Predictive Models for Cancer Therapies
Location
Uppsala, Sweden
Eligibility/Qualification
Required Qualifications:
- Doctoral degree (or equivalent foreign degree) in pharmacokinetic-pharmacodynamic modeling/pharmacometrics or a related field.
- Degree obtained within three years before the last application date (special circumstances like parental leave may allow for earlier degrees).
- Strong personal suitability and motivation to enhance model-based methods for cancer therapy development.
- Ability to work independently and take initiative, as well as function effectively in a group.
- Good command of English, both spoken and written.
Meritorious/Advantageous Qualifications:
- Documented experience in pharmacokinetic-pharmacodynamic modeling and simulation.
- Proficiency in modeling software such as NONMEM and R.
- Interest and skill in scientific writing.
- Experience with international collaborations.
Job Description
The successful candidate will be involved in a project focusing on developing platform approaches for PK-PD modelling in oncology. Key responsibilities include:
- Quantifying relationships between longitudinal tumor size dynamics and survival outcomes (PFS/OS).
- Modelling longitudinal hematological safety endpoints in patients with solid tumors undergoing treatment with anticancer therapies (e.g., combinations, antibody-drug candidates (ADCs)).
- Developing platform approaches to understand and quantify the relationship between longitudinal tumor size dynamics and survival in select tumors, assessing the impact of therapeutic agents and covariates.
- Incorporating methodological mitigations for immortal time bias within the modeling framework.
- Exploring platform approaches for jointly modeling longitudinal hematological safety endpoints.
The project aims to achieve new advances in predictive and quantitative models that are valuable for designing studies in oncology drug development, robustly characterizing benefit-risk profiles.
How to Apply
Applications must be submitted through Uppsala University’s recruitment system. Please do not send offers of recruitment or advertising services.
Last Date for Apply
September 30, 2026
