Postdoctoral Position in Stem Cell: The Department of Biomedicine (DBM) at the University of Basel is seeking a highly motivated postdoctoral researcher to join a team focused on cancer stem cells and their molecular regulation mechanisms. This position offers an exciting opportunity to contribute to groundbreaking research in a dynamic field with significant therapeutic implications.
Postdoctoral Position in Cancer Stem Cell Research
Designation
Postdoctoral Researcher
| Details | Information |
|---|---|
| Research Area | Cancer Stem Cell Research |
| Location | Department of Biomedicine, Mattenstrasse 28, Basel |
| Eligibility/Qualification | PhD in Biochemistry, Molecular Biology, or equivalent (MD PhDs welcome). Prior research experience in ribosomes is ideal but not mandatory. Fluency in English; German is a plus. |
| Job Description | The candidate will focus on isolating and characterizing SOX2/ribosome complexes, analyzing their molecular composition, transcript load, and structure using various advanced techniques. Collaboration with experts and extensive access to cutting-edge facilities is anticipated. |
| Last Date for Apply | [Insert Application Deadline Here] |
Research Area
- Investigation of cancer stem cells and the molecular mechanisms regulating their functionality.
- Focus on the role of SOX2 in transcription and translation, contributing to a deeper understanding of cancer progression.
Location
- Department of Biomedicine, Mattenstrasse 28, 4057 Basel, Switzerland.
Eligibility/Qualification
- Candidates must have a PhD in biochemistry, molecular biology, or a related field.
- MD PhDs with a strong interest in disease pathology are encouraged to apply.
- A solid research track in protein and RNA biochemistry is required. Experience in ribosome research is beneficial but not essential.
- A good command of English is necessary; knowledge of German is helpful.
- International experience (internship, PhD, or postdoctoral position abroad) is preferred.
Job Description
As a postdoctoral researcher, you will:
- Isolate and molecularly characterize SOX2/ribosome complexes.
- Analyze the molecular composition, transcript load, and structure of thus identified “stemness ribosomes.”
- Utilize advanced techniques such as density gradient centrifugation, ribosome profiling, affinity purification, RNA extraction, and library cloning.
- Collaborate with DBM core facilities and international partners, expanding technological capabilities (e.g., HPLC/MS, RIBOseq, cryo-EM).
- Contribute to the definition of pharmacological intervention sites at the SOX2/ribosome interface.
How to Apply
To apply, submit the following documents:
- CV
- A meaningful motivation letter
- Copies of relevant certificates (diplomas/degrees)
- One selected publication representative of your work
- Contact details of at least one reference (preferably your last employer or academic supervisor)
All applications will be processed, and selected candidates will be invited for an on-site interview.
For application submission, please visit: www.unibas.ch
Please replace “[Insert Application Deadline Here]” with the specific application deadline before posting.
