PomaLab at the Institute of Fundamental Technological Research (IPPT), Polish Academy of Sciences, is currently seeking a highly motivated researcher for a 3-year postdoctoral position focusing on computational biophysics.
Postdoctoral Position: Molecular Mechanisms of IDP Condensates, Polish Academy of Sciences, Poland
Position Overview
| Feature | Details |
| Designation | Postdoc / Assistant Professor |
| Research Area | Computational Biophysics (Multiscale Simulation) |
| Location | Warsaw, Poland |
| Project Duration | 36 Months |
| Start Date | January 1, 2027 |
| Application Deadline | September 30, 2026 |
Research Focus
Computational biophysics focusing on the multiscale modeling of IDP condensate transition into amyloid-like fibrils.
The successful candidate will join a multidisciplinary team investigating the molecular mechanisms governing the transition of intrinsically disordered protein (IDP) condensates into amyloid-like fibrils. This research is critical for understanding the early stages of neurodegenerative diseases.
The project utilizes a multiscale simulation framework, employing Martini 3 coarse-grained (CG) simulations adapted for IDPs, complemented by an extended GōMartini 3 model for controlled stabilization of sequence-specific secondary structures.
Job Description
- Investigate conformational rearrangements of individual protein chains.
- Model the nucleation of ordered $\beta$-strand–rich assemblies and their spatial organization within biomolecular condensates.
- Integrate experimental microscopy data for model parametrization and validation.
- Prepare scientific manuscripts and present research findings at international conferences.
- Contribute to the supervision and mentoring of PhD students.
Eligibility & Qualifications
While specific formal requirements are detailed in the full job posting (PDF), the role is suited for researchers with a background in computational biophysics, molecular modeling, or structural biology who are interested in the intersection of phase separation, protein aggregation, and neurodegeneration.
How to Apply
For full details on the requirements and application procedures, please review the full job posting (PDF). Interested candidates should contact Adolfo B. Poma directly at apoma@ippt.pan.pl.
