Postdoctoral Research Associate: Imperial College London is seeking a highly motivated Postdoctoral Research Associate to join our research group focused on the study of the subcellular signal organization of the glucagon receptor family (GLP-1R, GCGR, GIPR). This is an exciting opportunity to contribute to cutting-edge research using high-throughput screening techniques, high-resolution microscopy, and transgenic mouse models.
Designation
Postdoctoral Research Associate
| Details | Information |
|---|---|
| Job Number | MED04975 |
| Contract Type | Fixed term (24 months) |
| Work Pattern | Full time, Hybrid |
| Salary Range | £48,056 – £56,345 per annum |
| Location | Hammersmith Campus |
Research Area
- Subcellular signal organization of the glucagon receptor family (GLP-1R, GCGR, GIPR)
- Molecular mechanisms in pancreatic islets and other metabolically relevant cell types
Eligibility/Qualification
- PhD in molecular cell biology or a related subject
- Previous experience in GPCR signaling, high-resolution microscopy, molecular pharmacology, and/or in vivo mouse modeling
- Familiarity with pancreatic beta cell and islet biology
Job Description
As a Postdoctoral Research Associate, you will be responsible for:
- Elucidating the molecular mechanisms governing subcellular organization of glucagon receptor signaling.
- Utilizing techniques such as CRISPR/Cas9 gene editing, high-resolution microscopy, multi-omic approaches, and pharmacology methods.
- Analyzing glucose handling in transgenic mice and/or diet-induced diabetes models.
Ongoing projects include:
- Tissue selectivity of GLP-1R responses.
- Islet endocrine cell subtype-specific GLP-1R/GIPR signaling profiles.
- Gene variant characterization and functional validation.
- Investigating receptor family protein-protein interactions and mitochondrial function.
How to Apply
Interested candidates should apply through the Imperial College London’s careers portal. For more information, visit the lab website or contact Dr. Alejandra Tomas at a.tomas-catala@imperial.ac.uk with any questions.
Last Date to Apply
January 15, 2025
Join us at Imperial College London and become part of our vibrant research community focused on addressing significant scientific challenges and contributing to groundbreaking research in metabolism.
