Postdoctoral Research Scholar: The Purse Lab at San Diego State University (SDSU) invites applications for a Postdoctoral Research Scholar in synthetic organic chemistry and chemical biology. The selected candidate will contribute to projects centered on the design and synthesis of fluorescent nucleoside analogues and molecular probes for nucleic acid imaging and modification. This position offers comprehensive research training in organic synthesis, photophysics, and biophysical integration—preparing candidates for versatile scientific careers at the intersection of chemistry and biology.
Summary Table
| Position Title | Postdoctoral Research Scholar |
|---|---|
| Research Area | Synthetic Organic Chemistry, Chemical Biology, Nucleic Acid Chemistry |
| Location | Purse Lab, Department of Chemistry & Biochemistry, San Diego State University (SDSU), California, USA |
| Experience Required | 0–5 years of relevant postdoctoral or doctoral experience |
| Monthly Salary | USD $5,858.67 (non-negotiable) |
| Type of Position | Full-time, Research-based |
| Application Deadline | October 24, 2025 (Applications will be accepted until position is filled) |
| Contact Email | bpurse@sdsu.edu |
Designation
Postdoctoral Research Scholar
Research Area
- Synthetic Organic Chemistry
- Chemical Biology
- Nucleic Acid Chemistry and Modification
- Fluorescent Molecular Probe Design
- Nucleoside and Nucleobase Analogues
Location
Purse Lab, Department of Chemistry & Biochemistry,
San Diego State University (SDSU), California, USA
Eligibility / Qualification
Minimum Education & Experience
- Doctoral degree (Ph.D.) in an appropriate field.
- 0–5 years of relevant research experience.
Preferred Qualifications
- Ph.D. in Organic Chemistry, Chemical Biology, or a related discipline (completed before appointment).
- Proven research creativity and productivity (e.g., publications, conference presentations).
- Expertise in multi-step organic synthesis, purification, and structural characterization.
- Prior experience in nucleic acid chemistry, nucleoside modification, or fluorescent probe development.
- Familiarity with spectroscopic and photophysical assays (e.g., fluorescence spectroscopy, binding assays).
- Experience mentoring students and working collaboratively across disciplines.
Job Description
The Postdoctoral Research Scholar will:
- Design and perform multi-step organic syntheses of novel nucleoside/nucleobase analogues and related molecules.
- Develop and apply synthetic chemistry methods for oligonucleotides and nucleic acids.
- Purify and characterize compounds using NMR, MS, and chromatography techniques.
- Evaluate photophysical and spectroscopic properties of molecular probes.
- Collaborate with biological and biophysical researchers to integrate synthetic probes into nucleic acid constructs or assays.
- Analyze data, troubleshoot experiments, and interpret results.
- Prepare manuscripts, reports, and presentations; contribute to research planning and mentoring.
- Participate in lab meetings, departmental seminars, and outreach activities.
This role supports the lab’s mission to advance next-generation tools for nucleic acid imaging and RNA-centered therapeutics.
Core Competencies
- Expertise in synthetic organic chemistry and structural analysis.
- Strong problem-solving skills and experimental independence.
- Excellent communication and scientific writing abilities.
- Willingness to work in a collaborative, interdisciplinary environment.
- Interest in developing skills in chemical biology and photophysical probe design.
How to Apply
Interested candidates should submit the following to bpurse@sdsu.edu:
- A 2-page research summary including a statement of future research interests.
- A complete curriculum vitae (CV) with a list of publications.
- Names and contact information for three professional references.
Application Deadline: October 24, 2025 (applications received by this date will receive full consideration; position remains open until filled).
Additional Information
- The selected candidate must reside in California and live within a commutable distance from SDSU at the time of hire.
- Employment is contingent upon successful background verification.
- Equal Opportunity Statement:
San Diego State University Research Foundation is an equal opportunity employer, committed to fair treatment and equal access regardless of race, color, sex, ethnicity, national origin, disability, or any other status protected by law. Employment decisions are based solely on merit and qualifications.
