Postdoctoral Research Scientist: The University of Oxford, within the Nuffield Department of Clinical Neurosciences (NDCN), is seeking a highly motivated Postdoctoral Research Scientist to join Dr. Ruxandra Dafinca’s research group. This role focuses on investigating the synaptic role of mitochondria in neurons derived from ALS/FTD patients.
Designation
Postdoctoral Research Scientist
Table
| Detail | Information |
|---|---|
| Research Area | Mitochondrial Biology and Neuroscience |
| Location | Oxford, UK |
| Salary | £38,674 to £46,913 per annum |
| Contract Type | Fixed-Term/Contract |
| Work Hours | Full Time |
| Job Ref | 181846 |
| Contract Duration | 3 years |
Research Area
The focus of this research will be on human induced pluripotent stem cells (iPSCs) and their differentiation into motor neurons, particularly looking into the connections between mitochondrial dysfunction and synaptic dysregulation in neurodegenerative diseases such as ALS and FTD.
Eligibility/Qualification
- Completed (or near completion) a PhD/DPhil in Neuroscience, Biochemistry, or a relevant discipline.
- Strong laboratory experience, particularly in human iPSC differentiations and mitochondrial biology.
Job Description
The successful candidate will:
- Lead a project on mitochondrial roles in ALS/FTD neurons.
- Conduct laboratory experiments including iPSC differentiation, mitochondrial bioenergetics analysis, mass-spectrometry sample preparation, lentiviral transductions, and optogenetics.
- Contribute to the computational analysis of generated multi-omic data.
- Mentor and train postgraduate students and junior group members.
This position offers an exciting opportunity to advance strategies for neuronal analysis in health and disease, optimizing methods in a collaborative environment.
How to Apply
Interested candidates should send their application, including a CV and cover letter, to the NDCN HR Recruitment team at recruitment@ndcn.ox.ac.uk. For inquiries related to the project, contact Dr. Ruxandra Dafinca at ruxandra.dafinca@ndcn.ox.ac.uk.
Last Date for Apply
Applications should be received by 12.00 midday on Friday, 10th October 2025.
Note:
Interviews will be conducted shortly after the application deadline.
