Summary: The Califano lab in the Department of Systems Biology at Columbia University is seeking a highly qualified candidate for a Postdoctoral Research Scientist position. This role will involve advanced wet-lab experimentation and expertise in single-cell and spatial multi-omics technologies.
Designation
Postdoctoral Research Scientist
Table of Job Details
| Item | Details |
|---|---|
| Research Area | Single-cell Biology, Spatial Genomics, Systems Immunology, Cancer Biology, Stem Cell Biology |
| Location | Columbia University Irving Medical Center |
| Salary Range | $72,116 – $74,279 |
| Open Date | March 3, 2026 |
| Last Date to Apply | Until position filled |
Eligibility/Qualifications
Minimum Qualifications:
- PhD in molecular biology, immunology, cancer biology, genetics, epigenetics, stem cell biology, biomedical engineering, biochemistry, or a related field.
- Demonstrated record of first-author publications in peer-reviewed journals.
- Substantial experience with single-cell and/or spatial multi-omics methodologies.
Preferred Qualifications:
- Expertise in spatial transcriptomics, spatial ATAC-seq, multiplexed proteomic imaging, and multimodal data integration.
- Experience with CRISPR-mediated gene editing, perturbation screening, and gene regulatory analysis.
- Familiarity with regulatory and signaling network modeling and systems biology frameworks.
- Strong organizational, leadership, and collaborative skills.
Job Description
The Postdoctoral Research Scientist will:
- Develop and apply cutting-edge spatial and single-cell multi-omics technologies to interrogate regulatory and signaling networks in complex tissue ecosystems.
- Define cell-state transitions and regulatory circuits in both physiological and pathophysiological contexts, with a current focus on cancer.
- Design and implement CRISPR-based perturbation strategies to functionally test regulatory hypotheses derived from systems-level inference.
- Integrate genomic, epigenomic, and proteomic datasets to elucidate molecular determinants of cellular phenotypes.
The candidate will collaborate with multidisciplinary teams and contribute to consortium-scale projects, as well as participate in grant and fellowship applications.
How to Apply
Interested applicants should submit their application materials through Interfolio’s Faculty Search platform. The application must include:
- A cover letter
- CV
- Contact information for confidential letters of recommendation
Last Date to Apply
Until position filled
For more information, please visit the Columbia University careers page.
