Postdoctoral Researcher in 3D Genome: The Institute of Molecular Biology and Biotechnology, Faculty of Biology & Centre of Advanced Technologies at Adam Mickiewicz University in Poznań invites applications for a full-time Postdoctoral Researcher position within an NCN/DFG OPUS-LAP international project, in collaboration with University of Göttingen.
The successful candidate will join the Developmental Epigenetics Lab led by Dr hab. Michał R. Gdula, working on cutting-edge research focused on 3D genome re-organization during induced senescence in pancreatic cancer, integrating epigenomics, chromatin architecture, and long-read sequencing approaches.
Postdoctoral Researcher in 3D Genome Organization & Cancer Epigenetics
Summary Table
| Item | Details |
|---|---|
| Position | Postdoctoral Researcher |
| Project | 3D genome re-organization during induced senescence in pancreatic cancer |
| Host Institution | Adam Mickiewicz University in Poznań, Poland |
| Collaborating Institution | University of Göttingen, Germany |
| Funding Scheme | NCN/DFG OPUS-LAP |
| Duration | 3 years (1 year + 2-year extension) |
| Salary | ~112,000 PLN/year (gross); ~8,987 PLN/month + 13th salary |
| Start Date | 1 May 2026 |
| Application Deadline | 20 March 2026 |
Designation
Postdoctoral Researcher (Full-time)
Research Area
- Epigenetics and chromatin biology
- 3D genome organization
- Cellular senescence and pancreatic cancer
- Long-read sequencing (Nanopore)
- Functional genomics and cancer organoids
Location
Poznań, Poland
(Institute of Molecular Biology and Biotechnology & Centre of Advanced Technologies, Adam Mickiewicz University)
Job Description
The postdoctoral researcher will lead and execute an independent research project within the OPUS-LAP grant titled:
“3D genome re-organization during induced senescence in pancreatic cancer – insights from analysis of single chromatin fibers.”
Key responsibilities include:
- Planning and conducting molecular biology and cell culture experiments using pancreatic cancer organoids and degron cell lines
- Profiling epigenomic and chromatin architecture changes associated with HMGB2 interactors and senescence
- Performing and analyzing NGS and long-read Nanopore sequencing data
- Applying advanced chromatin and genome-wide techniques, including:
- Capture-C, Micro-C, PORE-C
- WGBS (methylome profiling)
- DamID (lamin associations)
- CUT&RUN (e.g., H3K9me3 heterochromatin mapping)
- Presenting results at group meetings, seminars, and international conferences
- Preparing manuscripts for publication in high-impact journals
Eligibility / Qualification
Essential Qualifications
- PhD in Molecular Biology, Genetics, or a closely related field
- Strong expertise in molecular biology and/or biochemistry techniques
- Experience with genomic approaches (e.g., RNA-seq, ChIP-seq, WGBS)
- At least one first-author peer-reviewed publication in a relevant field (e.g., epigenetics)
- Ability to work independently and lead a research project
- Excellent communication and interpersonal skills
Desirable Qualifications
- Experience with chromatin conformation capture techniques
- Bioinformatics and computational data analysis skills
- Hands-on experience with Nanopore sequencing
How to Apply
Interested candidates should submit a single PDF file containing:
- Cover letter
- Curriculum Vitae (CV)
- Contact details of three referees
Applications should be sent by email to:
📧 michal.gdula@amu.edu.pl
Informal inquiries are welcome.
Applicants must include the required GDPR consent statement as provided in the call.
Last Date for Apply
🗓 20 March 2026
Interviews of shortlisted candidates will be held shortly after the deadline.
