Postdoctoral Researcher in Bacterial Pathogens: The Weiss Lab at the Institute of Medical Microbiology, University of Zürich, is seeking a highly motivated Postdoctoral Researcher to investigate bacterial cell–cell interactions in disease-relevant contexts. The position focuses on advanced correlative cryo-electron tomography (cryo-ET) and in situ structural biology, combining infection biology with cutting-edge cryo-EM technologies in close collaboration with clinical partners.
Postdoctoral Researcher in Correlative Cryo-Electron Tomography of Bacterial Pathogens
Summary Table
| Category | Details |
|---|---|
| Position | Postdoctoral Researcher |
| Research Focus | Correlative cryo-ET of bacterial pathogens |
| Institution | Weiss Lab, Institute of Medical Microbiology, University of Zürich |
| Location | Zürich, Switzerland |
| Techniques | Cryo-ET, CLEM, Cryo-FIB, Infection Biology |
| Employment Type | Full-time Postdoctoral Position |
Designation
Postdoctoral Researcher (Postdoc)
Research Area
- Structural biology of bacterial pathogens
- Infection biology
- Correlative cryo-electron tomography (cryo-ET)
- In situ and multiscale imaging of disease mechanisms
Location
Institute of Medical Microbiology
University of Zürich
Zürich, Switzerland
Eligibility / Qualification
- PhD in Structural Biology, Microbiology, Biochemistry, Biophysics, or a related field
- Strong interest in infection biology and quantitative analysis of cellular ultrastructure
- Hands-on experience with cryo-EM/cryo-ET, FIB-SEM, or correlative imaging workflows is an advantage
- Familiarity with data processing and analysis pipelines
- Coding/scripting skills (e.g., Python, MATLAB, R) are a plus
- Independent, highly motivated, team-oriented, with excellent communication skills
Job Description
The successful candidate will:
- Study bacterial cell–cell interactions in disease-relevant contexts
- Perform bacterial infection assays (BSL2 and potentially BSL3)
- Apply advanced cryo-EM techniques, including:
- Plunge-freezing and high-pressure freezing
- Cryo-FIB milling with serial lift-out
- Cryo-electron tomography and subtomogram averaging
- Correlative light and electron microscopy (CLEM)
- Analyze and interpret structural data in collaboration with clinical and diagnostic partners
- Contribute to method development, publications, and conference presentations
How to Apply
Interested candidates should send the following documents:
- Curriculum Vitae (CV)
- Cover Letter (briefly outlining research background, key skills, and motivation)
Applications should be emailed to:
Dr. Gregor Weiss
📧 gweiss@imm.uzh.ch
Informal inquiries are welcome.
Last Date for Apply
Until the position is filled
