Postdoctoral Researcher in Cardiovascular Research: The Division of Cardiology at the Department of Medicine, Solna, Karolinska Institutet invites applications for a Postdoctoral Researcher position to join Associate Professor Zhichao Zhou’s research team. The role involves contributing to cutting-edge research on cardiovascular complications associated with type 2 diabetes, focusing on novel disease mechanisms, therapeutic targets, and biomarkers to prevent and predict cardiovascular dysfunction. The position is located at BioClinicum, Karolinska Institutet, which offers a highly collaborative and modern research environment.
Designation
Postdoctoral Researcher
About the Research Area
The project focuses on type 2 diabetes and its associated vascular complications, particularly investigating the role of red blood cell-derived non-coding RNAs in vascular dysfunction. Research methods include a combination of clinical and molecular-based investigations using a variety of models:
- Materials Used: Well-characterized patient samples, rodent diabetic models, gene-modified mouse models, and cell culture models.
- Techniques Employed:
- In vitro: Isolation of red blood cells, extracellular vesicles, immunohistochemistry, cell culture, Western blot, and qPCR.
- Ex vivo: Vessel reactivity assessment using Wire myograph.
- In vivo: Animal experiments using rat and mouse models.
Duration of Appointment: 2 years, with a possible extension of up to 2 additional years.
Job Location
Institution: Karolinska Institutet
Department: Department of Medicine, Division of Cardiology
Research Hub: BioClinicum, Solna, Stockholm, Sweden
Eligibility/Qualification
| Criteria | Details |
|---|---|
| Educational Qualification | A PhD or a foreign degree equivalent to a Swedish PhD (must be completed before the employment decision). |
| Field of Study | Cardiovascular research, vascular biology, or related fields. |
| Research Background | Strong research history in experimental and translational cardiovascular research documented by publications. |
| Technical Expertise | – Hands-on experience in isolated artery studies and/or animal work. – Proficiency in laboratory techniques such as Western blotting, immunohistochemistry, and cell culture. – Knowledge/experience with non-coding RNA studies is considered a merit. |
| Additional Skills | Creative thinker, strong communication skills, team-player, and fluency in English (written and spoken). |
| Advantage | Completed doctoral degree within the last three years, unless there are special circumstances. |
Job Description
As a postdoctoral researcher, you will participate in the following:
- Experimental design and execution using advanced molecular and cellular techniques.
- Conducting studies in in vitro, ex vivo, and in vivo settings.
- Integration and handling of patient and animal models.
- Preparing research data for presentations and publications.
- Collaborating within the research team and contributing to overall project goals.
What We Offer
Karolinska Institutet provides a creative, inspiring, and internationally renowned research environment. The Cardiovascular Theme is supported by state-of-the-art facilities for cell culture, molecular biology, functional analysis, and microscopy. Being a part of KI means access to cross-disciplinary knowledge and interaction with leading scientists in medicine and healthcare.
Additional benefits include entitlements tied to KI’s collective agreement as a state university in Sweden.
How to Apply
Applications are to be submitted via the Varbi Recruitment System. Ensure to include the following documents (in English or Swedish):
- PhD Certificate
- Complete CV (detailing current position, title of thesis, date of thesis defense, academic distinctions, previous academic roles, and committee work)
- Full list of publications
- A summary of current work (maximum one page)
Last Date to Apply
Deadline: March 5, 2025, 11:59 PM CET
Contact Information
For inquiries, please contact:
- Zhichao Zhou, Associate Professor, E-mail: zhichao.zhou@ki.se
- Union Representatives:
- Louisa Cheung, SACO: Louisa.Cheung@ki.se
- Farzad Hedayaty, SACO-s: Farzad.Hedayaty@ki.se
- Maria Eldh, OFR: Maria.Eldh@ki.se
Reference Number: STÖD 2-622/2025
Join us in advancing medical research and making a difference in global healthcare!
